15098-69-8

Basic information

• Product Name: BOC-LYS(BOC)-OH DCHA
• Synonyms: N2,N6-Bis-(tert-butoxycarbonyl)-L-lysine dicyclohexylamine salt;Bis-Boc-Lysine, DCHA;N-.ALPHA.,E-DI-BOC-L-LYSINE DICYCLOHEXYLAMINE SALT;Nalpha,Nepsilon-di-tert-BOC-L-lysine dicyclohexylammonium;Boc-Lys(Boc)-Ohcha;N,N'-Bis(tert-butoxycarbonyl)-L-lysine dicyclohexylamine (1:1);N,N'-Di-Boc-L-lysine dicyclohexylamine salt;Boc-Lys(Boc)-OH dicyclohexammonium salt
• CAS NO: 15098-69-8
• Molecular Formula: C28H53N3O6
• Molecular Weight: 527.74
• EINECS: 239-150-9
• Product Categories: AMINOACIDS DERIVATIVES;Amino Acid Derivatives;Amino Acids;Lysine [Lys, K];Boc-Amino Acids and Derivative;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids
• Mol File: 15098-69-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 139-143℃
• Boiling Point: 672.6 °C at 760 mmHg
• Flash Point: 360.6 °C
• Appearance: White/Solid
• Vapor Pressure: 7.74E-20mmHg at 25°C
• Storage Temp.: −20°C
• Solubility: almost transparency in Methanol
• CAS DataBase Reference: BOC-LYS(BOC)-OH DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-LYS(BOC)-OH DCHA(15098-69-8)
• EPA Substance Registry System: BOC-LYS(BOC)-OH DCHA(15098-69-8)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 15098-69-8(Hazardous Substances Data)

Usage

Description

BOC-LYS(BOC)-OH DCHA, also known as Boc-Lys(Boc)-OH dicyclohexammonium salt, is a protected form of L-lysine (L468895) that is primarily used in the preparation of dendritic peptide bolaamphiphiles for siRNA delivery. It is characterized by its white to off-white powder appearance.

Uses

Used in Pharmaceutical Industry:
BOC-LYS(BOC)-OH DCHA is used as a key component in the synthesis of dendritic peptide bolaamphiphiles for the purpose of siRNA delivery. This application is significant because it aids in the development of targeted gene silencing therapies, which have the potential to treat various diseases at the genetic level.
Used in Gene Therapy:
BOC-LYS(BOC)-OH DCHA is used as a building block for the development of dendritic peptide bolaamphiphiles, which are essential for the efficient delivery of small interfering RNA (siRNA) molecules. This application is crucial in gene therapy, as it enables the specific silencing of disease-causing genes, offering a promising approach to treat genetic disorders and other conditions.
Used in Drug Delivery Systems:
BOC-LYS(BOC)-OH DCHA is used as a component in the design and synthesis of advanced drug delivery systems, particularly those involving siRNA delivery. Its role in these systems is to facilitate the targeted delivery of therapeutic molecules, enhancing their bioavailability and therapeutic outcomes. This application is vital in improving the efficacy and safety of treatments for various diseases.

InChI:InChI=1/C16H30N2O6.C12H23N/c1-15(2,3)23-13(21)17-10-8-7-9-11(12(19)20)18-14(22)24-16(4,5)6;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11H,7-10H2,1-6H3,(H,17,21)(H,18,22)(H,19,20);11-13H,1-10H2/t11-;/m0./s1