15104-07-1

Basic information

• Product Name: Piperidine, 1-nitroso-4-(phenylmethyl)-
• CAS NO: 15104-07-1
• Molecular Formula: C12H16N2O
• Molecular Weight: 204.272
• Mol File: 15104-07-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-nitroso-4-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-nitroso-4-(phenylmethyl)-(15104-07-1)
• EPA Substance Registry System: Piperidine, 1-nitroso-4-(phenylmethyl)-(15104-07-1)

Safety Data

• Hazardous Substances Data: 15104-07-1(Hazardous Substances Data)

Upstream product

• 31252-42-3 4-benzylpyperidine 

Downstream Products

• 31252-42-3 4-benzylpyperidine 

Relevant articles and documents

Direct Transformation of Arylamines to Aryl Halides via Sodium Nitrite and N-Halosuccinimide

A one-pot universal approach for transforming arylamines to aryl halides via reaction with sodium nitrite (NaNO2) and N-halosuccinimide (NXS) in DMF at room temperature under metal- and acid-free condition is described. This new protocol that is complementary to the Sandmeyer reaction, is suggested to involve the in situ generation of nitryl halide induce nitrosylation of aryl amine to form the diazo intermediate which is halogenated to furnish the aryl halide.

Selective N-nitrosation of amines, N-alkylamides and N-alkylureas by N2O4 supported on cross-linked polyvinylpyrrolidone (PVP-N2O4)

N2O4 was supported on the cross-linked polyvinylpyrrolidone (PVP) to afford a solid, stable and recyclable nitrosating agent. This reagent shows excellent selectivity for N-nitrosation of dialkyl amines in the presence of diaryl-, arylalkyl-, trialkylamines and also for secondary amides in dichloromethane at room temperature under mild and heterogeneous conditions. Also N-nitroso-N-alkyl amides can be selectively prepared in the presence of primary amides and N-phenylamides under similar reaction conditions. Selective N-nitrosation or dealkylation and N-nitrosation of tertiary amines can also be performed by this reagent.