151132-82-0 Usage
General Description
"(2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid" is a complex organic compound characterized by its fluorenylmethyloxycarbonyl (Fmoc) protective group. A compound such as this typically arises in the realm of peptide synthesis, where Fmoc protection is often used to enable the coupling of amino acids in a controlled and stepwise manner. (2S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid includes two Fmoc-protected amino groups, one attached to the 4-position and one attached to the 2-position of the butanoic acid core. The protective groups can be removed under specific conditions to reveal the amino groups for subsequent coupling reactions. The phenylmethoxy group is another notable feature of this compound's structure.
Check Digit Verification of cas no
The CAS Registry Mumber 151132-82-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,1,3 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 151132-82:
(8*1)+(7*5)+(6*1)+(5*1)+(4*3)+(3*2)+(2*8)+(1*2)=90
90 % 10 = 0
So 151132-82-0 is a valid CAS Registry Number.
InChI:InChI=1S/C27H26N2O6/c30-25(31)24(29-27(33)34-16-18-8-2-1-3-9-18)14-15-28-26(32)35-17-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,23-24H,14-17H2,(H,28,32)(H,29,33)(H,30,31)/t24-/m0/s1
151132-82-0Relevant articles and documents
Synthesis and evaluation of novel dipeptide-bound 1,2,4-thiadiazoles as irreversible inhibitors of guinea pig liver transglutaminase.
Marrano,de Macedo,Gagnon,Lapierre,Gravel,Keillor
, p. 3231 - 3241 (2007/10/03)
Herein we report the synthesis and evaluation of 14 novel peptides as potential irreversible inactivators of guinea pig liver transglutaminase (TGase). These peptides were designed to resemble Cbz-L-Gln-Gly, known to be a good TGase substrate, and to include a 1,2,4-thiadiazole group. The side chain length of the amino acid residue bearing the inhibitor group was also varied in order to permit investigation of this effect. Their inactivation rate constants were measured using a direct continuous spectrophotometric method and were found to vary between 0.330 to 0.89 microM(-1) min(-1).
Metal Chelating Amino Acids in the Design of Peptides and Proteins. Synthesis of Nα-Fmoc/But Protected Amino Acids Incorporating Aminodiacetic Acid Moiety.
Kazmierski, Wieslaw M.
, p. 4493 - 4496 (2007/10/02)
The synthesis of Fmoc/But protected amino acid chelators 14, 15, 16 and 24 is described.With respect to their Boc/Bzl derivatives, the title compounds offer synthetic advantage: peptide Ac-Ada(1)-Ala3-Ada(1)-Ala4-Glu-Lys-NH2 was assembled by So
