15121-75-2

Basic information

• Product Name: 2(5H)-Furanone, 3-methyl-5-phenyl-
• CAS NO: 15121-75-2
• Molecular Formula: C11H10O2
• Molecular Weight: 174.199
• Mol File: 15121-75-2.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 3-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 3-methyl-5-phenyl-(15121-75-2)
• EPA Substance Registry System: 2(5H)-Furanone, 3-methyl-5-phenyl-(15121-75-2)

Safety Data

• Hazardous Substances Data: 15121-75-2(Hazardous Substances Data)

Upstream product

• 53138-45-7 5-phenyl-2,5-dihydrofuran-2-one 
• 79-22-1 methyl chloroformate 
• 74-88-4 methyl iodide 
• 1771-65-9 2-methyl-4-oxo-4-phenylbutanoic acid 
• 22122-36-7 3-methyl-5H-furan-2-one 
• 176041-42-2 triisopropyl((3-methylfuran-2-yl)oxy)silane 
• 98-80-6 phenylboronic acid 
• 58109-40-3 diphenyliodonium hexafluorophosphate 
• 616-02-4 citraconic acid anhydride 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 143901-75-1 3-methyl-5-phenyl-3-(phenylthio)dihydrofuran-2(3H)-one 
• 53138-48-0 5-phenyl-3-(phenylthio)dihydrofuran-2(3H)-one 
• 96-09-3 styrene oxide 

Downstream Products

• 1160526-81-7 5-(3-isopropoxyphenyl)-3-methyl-5-phenylfuran-2-one 
• 436147-10-3 (S)-(-)-3-methyl-5-phenylfuran-2(5H)-one 
• 504432-48-8 (R)-(+)-3-methyl-5-phenylfuran-2(5H)-one 
• 130856-90-5 (3R,5S)-3-methyl-5-phenyl-4,5-dihydrofuran-2(3H)-one 
• 844886-81-3 3-methyl-5-phenyl-2,5-dihydro-2-furanol 

Relevant articles and documents

A facile solid-phase synthesis of substituted 2(5H)-furanones with sulfone traceless linker

A novel solid-phase synthetic method for substituted 2(5H)-furanones with traceless sulfone linker strategy has been developed. The products were obtained in good yields and excellent purities.

CuCl-catalyzed cycloisomerization reaction of 1,2-allenyl carboxylic acids. A cost-effective synthesis of β-unsubstituted butenolides

Fourteen examples of 2,3-butadienoic acids were synthesized according to the known procedures and their high-yielding CuCl-catalyzed cycloisomerization reaction to afford butenolides were described.

Diastereoselective Alkene Hydroesterification Enabling the Synthesis of Chiral Fused Bicyclic Lactones

Palladium-catalysed diastereoselective hydroesterification of alkenes assisted by the coordinative hydroxyl group in the substrate afforded a variety of chiral γ-butyrolactones bearing two stereocenters. Employing the carbonylation-lactonization products as the key intermediates, the route from the alkenes with single chiral center to chiral THF-fused bicyclic γ-lactones containing three stereocenters was developed.

Lewis base-catalyzed electrophilic lactonization of selenyl bromide resin and facile solid-phase synthesis of furan-2(5H)-one derivatives

A facile solid-phase synthesis approach was developed for the rapid synthesis of multi-substituted furan-2(5H)-one derivatives libraries. The synthetic strategy included the selenyl bromide resin-induced electrophilic lactonization catalyzed by Lewis base, lithiation, nucleophilic substitution and oxidation-elimination of the selenium resins. The advantages of the new method are good yields, high purity, straightforward operations and high diversity of the products, lack of odor, and good stability of the selenium resins. Copyright