151238-04-9Relevant articles and documents
Effect of substrate structure on N-methylimidazole-catalyzed formation of thiosemicarbazides
Yanchuk
, p. 450 - 452 (2007/10/03)
The kinetics of the N-methylimidazole-catalyzed reactions of aryl isothiocyanates with diphenylphosphinic hydrazide in benzene at 25°C were studied. N-Methylimidazole exhibits a high catalytic activity depending on the structure of the isothiocyanates. Th
EFFECT OF THE STRUCTURE OF ARYL ISOTHIOCYANATES ON THE PYRIDINE-CATALYZED FORMATION OF PHOSPHORUS-CONTAINING THIOSEMICARBAZIDES
Yanchuk, N. I.
, p. 591 - 593 (2007/10/02)
The effect of the structure of aromatic isothiocyanates on their pyridine-catalyzed reaction with diphenylphosphinic hydrazide in benzene at 25 deg C was studied.In general, the overall process of thiosemicarbazide formation involves two concurrent reactions: an uncatalytic second-order reaction and a catalytic third-order one.A quantitative estimation was made of the effect of substituents in the molecules of aryl isothiocyanates on the rates of the uncatalytic and catalytic reactions.Aromatic isothiocyanates are more sensitive to the electronic effects of substituents in the catalytic than in the uncatalytic process.On the basis of the experimental data, an explanation for this pattern of behavior is proposed.