151250-69-0Relevant articles and documents
A new synthesis of N-substituted-1,2,3,4-tetrahydro-4-phenylisoquinolin-3-ones
Coskun,Sumengen
, p. 1393 - 1402 (2007/10/02)
1,2,3,4-Tetrahydro-4-phenylisoquinolin-3-ones 3 are obtained from appropriate N,N-disubstituted phenylacetamides 1, using lead tetraacetate (LTA) as oxidant and Lewis or proton acids as cyclizing agents. The methods for this conversion could be one stage (method B or C), or two stages (method A). The latter method was particularly developed to explain the mechanism of the reaction.