15128-91-3 Usage
Description
2,6-DINITRO-3-HYDROXYPYRIDINE, also known as 2,6-Dinitro-3-pyridinol, is an organic compound with the molecular formula C5H3N3O4. It is characterized by the presence of a pyridine ring with hydroxyl, nitro, and hydroxyl groups at the 3rd, 2nd, and 6th positions, respectively. 2,6-DINITRO-3-HYDROXYPYRIDINE is known for its potential applications in various fields, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2,6-DINITRO-3-HYDROXYPYRIDINE is used as a reagent for the synthesis of pyrimidinediamine derivatives. These derivatives have the potential to act as Syk protease inhibitors, which are important targets for drug development. Inhibiting Syk protease can be beneficial in the treatment of various diseases, as it plays a role in the regulation of immune responses and inflammatory processes.
In the context of drug development, 2,6-DINITRO-3-HYDROXYPYRIDINE serves as a key intermediate in the synthesis of compounds that can modulate the activity of Syk protease. By targeting this enzyme, these synthesized compounds may help in the development of novel therapeutics for a range of diseases, including autoimmune disorders and inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 15128-91-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,2 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15128-91:
(7*1)+(6*5)+(5*1)+(4*2)+(3*8)+(2*9)+(1*1)=93
93 % 10 = 3
So 15128-91-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H3N3O5/c9-3-1-2-4(7(10)11)6-5(3)8(12)13/h1-2,9H
15128-91-3Relevant articles and documents
Reactivity of heterocyclic compounds in nitration. 8. Nitration of 3-hydroxypyridine and its substituted forms
Falyakhov,Gil'manov,Sharnin,Bol'shakova
, p. 830 - 832 (1998)
Nitration of 3-hydroxypyridine and its substituted forms has been studied under various conditions. It is shown that, depending on the reaction temperature and the nitrating agent, the end products of the synthesis can be 3-hydroxy-2,6-dinitropyridine or 3-hydroxy-2,4,6-trinitropyridine. The possibility of substitutional nitration of iodine derivatives of 2- and 3-hydroxypyridine is demonstrated. 1999 Kluwer Academic/Plenum Publishers.
