151338-05-5

Basic information

• Product Name: 2-methoxy-3-methyl-7-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(3H)-one
• Synonyms: 4(3H)-Pteridinone, 2-methoxy-3-methyl-7-((1R,2S)-1,2,3-trihydroxypropyl)-; 4(3H)-Pteridinone, 2-methoxy-3-methyl-7-[(1R,2S)-1,2,3-trihydroxypropyl]-
• CAS NO: 151338-05-5
• Molecular Formula: C₁₁H₁₄N₄O₅
• Molecular Weight: 282.2527
• Mol File: 151338-05-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 596.2°C at 760 mmHg
• Flash Point: 314.3°C
• Density: 1.64g/cm³
• Vapor Pressure: 4.64E-15mmHg at 25°C
• Refractive Index: 1.691
• CAS DataBase Reference: 2-methoxy-3-methyl-7-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-3-methyl-7-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(3H)-one(151338-05-5)
• EPA Substance Registry System: 2-methoxy-3-methyl-7-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(3H)-one(151338-05-5)

Safety Data

• Hazardous Substances Data: 151338-05-5(Hazardous Substances Data)

Upstream product

• 87-72-9 L-(+)-arabinose 
• 85357-27-3 5,6‐diamino‐2‐methoxy‐3‐methylpyrimidin‐4(3H)‐one 
• 328553-61-3 6-amino-5-N-β-L-arabinopyranosylamino-2-methoxy-3-methylpyrimidin-4(3H)-one 

Relevant articles and documents

Synthesis of 5-N-glycosylaminopyrimidines. A new class of compounds with potential anti-aids activity

Reactions between 5,6-diaminopyrimidines 1a-c and pentoses 2a-e yield 5-N-glycosylaminopyrimidines or 7-polyhydroxyalkylpteridines, depending on the presence or absence of acetic acid. The "in vitro" anti-HIV activity of 6-amino-2-methoxy-3-methyl-5-N-D-ribosylaminopyrimidin-4(3H)-one 3e, 6-amino-2-methoxy-3-methyl-5-N-β-D-xylopyranosylaminopyrimidin-4(3H)-one 3f, and 6-amino-2-methylthio-5-N-β-L-xylopyranosylminopyrimidin-4(3H)-one 3k, appears to be promising.