151451-82-0Relevant articles and documents
A palladacyclic N-heterocyclic carbene system used to probe the donating abilities of monoanionic chelators
Yan, Xuechao,Feng, Rui,Yan, Chunhui,Lei, Peng,Guo, Shuai,Huynh, Han Vinh
, p. 7830 - 7838 (2018)
A series of NHC-containing [C^N]- or [C^C′]-type palladacyclic complexes of the general formula [PdBr(iPr2-bimy)(L^X)] (5-8, 11, 12, iPr2-bimy = 1,3-diisopropylbenzimidazolin-2-ylidene) have been synthesized and fully characterized. Using these complexes, the donating abilities of monoanionic chelators were probed for the first time. The [C^N]-type palladacycles 5-8 were prepared from acetato-bridged dipalladium complexes [Pd(μ-CH3COO)(C^N)]2 (1-4) and iPr2-bimy·H+Br-as precursors. In the case of the [C^C′]-type NHC palladacycles (11, 12), the hetero-bis(NHC) complexes trans-[PdBr2(iPr2-bimy)(trz)] (8, 9, trz = 1,2,3-triazolin-5-ylidene) containing the iPr2-bimy probe were first prepared followed by acetate-assisted cyclopalladations. The 13Ccarbene NMR signals of the iPr2-bimy ligands in all complexes (i.e. HEP and HEP2 values) are found to rationally reflect the donating abilities of the incorporated trz or [L^X]-type chelators with the exception of the Bzpy ligand (Bzpy = 2-(2-pyridinylmethyl)phenyl-C,N). This has been attributed to its larger bite angle, the resulting varied coordination geometry and the lack of electronic delocalization between the two donor units. The donicities of [L^X]-type chelators studied in this work were found to surpass those of all other bidentate ligands evaluated by HEP2 thus far.
Using Small Molecules to Enhance P450 OleT Enzyme Activity in Situ
Zhang, Libo,Ma, Dumei,Yin, Yingwu,Wang, Qian
supporting information, p. 8940 - 8945 (2021/05/28)
Cytochrome P450 OleT is a fatty acid decarboxylase that catalyzes the production of olefins with biofuel and synthetic applications. However, the relatively sluggish catalytic efficiency of the enzyme limits its applications. Here, we report the application of a novel class of benzene containing small molecules to improve the OleT activity. The UV-Vis spectroscopy study and molecular docking results confirmed the high proximity of the small molecules to the heme group of OleT. Up to 6-fold increase of product yield has been achieved in the small molecule-modulated enzymatic reactions. Our work thus sheds the light to the application of small molecules to increase the OleT catalytic efficiency, which could be potentially used for future olefin productions.
A ferrocene functionalized Schiff base containing Cu(ii) complex: Synthesis, characterization and parts-per-million level catalysis for azide alkyne cycloaddition
Gayen, Firdaus Rahaman,Ali, Abdul Aziz,Bora, Debashree,Roy, Saptarshi,Saha, Supriya,Saikia, Lakshi,Goswamee, Rajib Lochan,Saha, Biswajit
supporting information, p. 6578 - 6586 (2020/06/08)
Atom economy is one of the major factors in developing catalysis chemistry. Using the minimum amount of catalyst to obtain the maximum product yield is of the utmost priority in catalysis, which drives us to use parts-per-million (ppm) levels of catalyst