1514927-09-3

Basic information

• Product Name: 1-(8-quinolinyl)-4-benzylazetidinone
• Synonyms: 1-(8-quinolinyl)-4-benzylazetidinone
• CAS NO: 1514927-09-3
• Molecular Weight: 288.349
• Mol File: 1514927-09-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(8-quinolinyl)-4-benzylazetidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(8-quinolinyl)-4-benzylazetidinone(1514927-09-3)
• EPA Substance Registry System: 1-(8-quinolinyl)-4-benzylazetidinone(1514927-09-3)

Safety Data

• Hazardous Substances Data: 1514927-09-3(Hazardous Substances Data)

Upstream product

• 1449300-08-6 4-phenyl-N-(quinolin-8-yl)butanamide 

Relevant articles and documents

Stereoselective synthesis of diazabicyclic β-lactams through intramolecular amination of unactivated C(sp3)-H bonds of carboxamides by palladium catalysis

An efficient C(sp3)-H bond activation and intramolecular amination reaction via palladium catalysis at the β-position of carboxyamides to make β-lactams was described. The investigation of the substrate scope showed that the current reaction conditions favored activation of the β-methylene group. Short sequences were developed for preparation of various diazabicyclic β-lactam compounds with this method as the key step from chiral proline and piperidine derivatives.

Palladium-catalyzed unactivated c(sp3)-h bond activation and intramolecular amination of carboxamides: A new approach to β-lactams

An efficient method to synthesize the β-lactams with high regioselectivity via Pd-catalyzed C(sp3)-H bond activation and intramolecular amination of simple and readily available aminoquinoline carboxamides was demonstrated. C6F5I plays a signif