1515830-40-6

Basic information

• Product Name: 3-(4-fluorophenyl)-1-phenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl
• CAS NO: 1515830-40-6
• Molecular Weight: 302.331
• Mol File: 1515830-40-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)-1-phenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-1-phenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl(1515830-40-6)
• EPA Substance Registry System: 3-(4-fluorophenyl)-1-phenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl(1515830-40-6)

Safety Data

• Hazardous Substances Data: 1515830-40-6(Hazardous Substances Data)

Upstream product

• 1496-02-2 4-fluoro-N′-phenylbenzohydrazide 
• 1493-27-2 ortho-nitrofluorobenzene 
• 1515829-92-1 4-Fluoro-N′-(2-nitrophenyl)-N′-phenylbenzohydrazide 

Relevant articles and documents

Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N ′-(Het)aryl- N ′-[2-nitro(het)aryl]hydrazides

A two-step route to 1,3-disubstituted benzo- and pyrido-fused 1,2,4-triazinyl radicals is presented. The route involves the N′-(2-nitroarylation) of easily prepared N′-(het)arylhydrazides via nucleophilic aromatic substitution of 1-halo-2-nitroarenes, which in most cases gives N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides in good yields. Mild reduction of the nitro group followed by an acid-mediated cyclodehydration gives the fused triazines, which upon alkali treatment afford the desired radicals. Fifteen examples of radicals are presented bearing a range of substituents at N-1, C-3, and C-7, including the pyrid-2-yl and 8-aza analogues. This route to the N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides, which works well with benzo- and picolinohydrazides, required a modification for aceto- and trifluoroacetohydrazides that involved a multistep synthesis of asymmetrically 1,1-diaryl-substituted hydrazines.