151629-69-5Relevant articles and documents
Synthesis of Annulated γ-Lactams via Intramolecular 1,3-Dipolar Cycloadditions of Functionalized N-Allyl α-Diazo Amides
Minami, Toru,Kamitamari, Masashi,Utsunomiya, Tomohisa,Tanaka, Tetsuya,Ichikawa, Junji
, p. 1496 - 1500 (2007/10/02)
N-Allyldiazoacetamides containing a phosphinyl group at the α-position underwent the intramolecular 1, 3-cycloaddition, followed by 1,3-hydrogen shift to afford 6a-diethoxyphosphinyl-3a,4,5,6a-tetrahydropyrrolopyrazol-6(1H)-ones in 74-78percent yields, while the corresponding α-phenylthio amide produced 1-phenylthio-3-azabicyclohexan-2-one in 74percent yield via extrusion of N2 from the intramolecular 1,3-cycloadduct.In the application of these compounds to the conversion of functionality, the former gave a fused tricyclic heterocycle and the latter gave deallylated compounds.