1516902-86-5Relevant articles and documents
Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2
Winter, Evelyn,Lecerf-Schmidt, Florine,Gozzi, Gustavo,Peres, Basile,Lightbody, Mark,Gauthier, Charlotte,Ozvegy-Laczka, Csilla,Szakacs, Gergely,Sarkadi, Balazs,Creczynski-Pasa, Ta?nia B.,Boumendjel, Ahcène,Di Pietro, Attilio
, p. 9849 - 9860 (2014/01/17)
We recently identified a chromone derivative, 5-(4-bromobenzyloxy)-2-(2-(5- methoxyindolyl)ethyl-1-carbonyl)-4H-chromen-4-one, named here as chromone 1, as a potent, selective, nontoxic, and nontransported inhibitor of ABCG2-mediated drug efflux (Valdamer