15177-67-0

Basic information

• Product Name: TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
• Synonyms: TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER;TRANS-4-CARBOMETHOXYCYCLOHEXANE-1-CARBOXYLIC ACID;4(METHOXY CARBONYL) CYCLOHEXANE CARBOXYLIC ACID;TRANS-4-(METHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID;(1r,4r)-4-(methoxycarbonyl)cyclohexanecarboxylic acid;Methyl trans-4-carboxycyclohexane-1-carboxylate;trans-4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid;TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL
• CAS NO: 15177-67-0
• Molecular Formula: C₉H₁₄O₄
• Molecular Weight: 186.21
• EINECS: 210-614-2
• Product Categories: API
• Mol File: 15177-67-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 126.0 to 130.0 °C
• Boiling Point: 303.145 °C at 760 mmHg
• Flash Point: 118.334 °C
• Appearance: /
• Density: 1.191 g/cm³
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER(15177-67-0)
• EPA Substance Registry System: TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER(15177-67-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 15177-67-0(Hazardous Substances Data)

Usage

Description

TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER, also known as a carboxylic acid ester derivative, is an organic compound with the molecular formula C9H14O4. It is characterized by its unique cyclic structure and ester functional group, which contributes to its chemical properties and potential applications.

Uses

Used in Chemical Synthesis:
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER is used as an organic reagent for the synthesis of various chemical compounds. Its ester functional group allows for further reactions and modifications, making it a versatile building block in organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER is used as a key intermediate in the production of certain drugs. Its unique structure and reactivity enable the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Material Science:
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER is also utilized in the field of material science, where it can be employed in the development of novel polymers and other advanced materials. Its cyclic structure and ester group provide opportunities for creating materials with specific properties, such as enhanced strength, flexibility, or chemical resistance.
Used in Research and Development:
In research and development, TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER serves as a valuable compound for studying the properties and behavior of carboxylic acid esters. It can be used to explore new reaction pathways, investigate the effects of structural modifications, and develop a deeper understanding of the underlying chemistry.

InChI:InChI=1/C9H14O4/c1-13-9(12)7-4-2-6(3-5-7)8(10)11/h6-7H,2-5H2,1H3,(H,10,11)/t6-,7+

Upstream product

• 619-82-9 trans-hexahydroterephthalic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 94-60-0 dimethyl 1,4-cyclohexane dicarboxylate 
• 3399-22-2 dimethyl 1,4-cyclohexanedicarboxylate 
• 186581-53-3 diazomethane 
• 67-56-1 methanol 

Downstream Products

• 4630-82-4 methyl cyclohexylcarboxylate 
• 3399-22-2 dimethyl 1,4-cyclohexanedicarboxylate 

Relevant articles and documents

Magnetic Field Dependent Reaction Yields from Radical Ion Pairs Linked by a Partially Rigid Aliphatic Chain

The electron donor-acceptor compound pyrene-(CH2)3-cyclohexane-(CH2)3-dimethylaniline, abbreviated as Py3(C6)3DMA, has been investigated.Photoinduced electron transfer leads to the singlet radical ion pair Py-3(C6)3DMA+.An extraordinary large and distinct magnetic field effect is observed in the yield of the locally excited triplet state of the pyrene moiety, the recombination product of the triplet radical ion pair.The half-width of the "J-resonance" maximum in the magnetic field dependent triplet yield curve is just 66 G, corresponding to 7.7*10-7 eV or 6.2*10-3 cm-1.This is due to the influence of the rigid trans-cyclohexane part in the aliphatic chain, which leads to a reduced intramolecular mobility and to a narrow probability distribution of the radical ion pair distance, as predicted by Monte-Carlo computer simulations.The magnetic field dependence of the triplet generation is further transmitted to secondary reactions like triplet-triplet annihilation, thus leading to a magnetic field dependent delayed fluorescence and to a delayed excimer fluorescence.

BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING SAME

Provided herein are compounds and methods for modulating abnormal repeat expansions of gene sequences. More particularly, provided are inhibitors of RNA and the uses of such inhibitors in regulating nucleotide repeat expansions, e.g., to treat Myotonic Dystrophy Type 1 (DM1 ), Myotonic Dystrophy Type 2 (DM2), Fuchs dystrophy, Huntington Disease, Amyotrophic Lateral Sclerosis, or Frontotemporal Dementia.

TRICYCLIC PYRROLOPYRIDINE COMPOUND, AND JAK INHIBITOR

To provide a novel tricyclic pyrrolopyridine compound having a JAK inhibitory activity and useful for prevention, treatment and/or improvement of particularly autoimmune diseases, inflammatory diseases and allergic diseases. A novel tricyclic pyrrolopyridine compound represented by the formula (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof: wherein the respective substituents are defined in detail in the specification, and R1 is a C1-6 alkyl group or the like, R2 is a hydrogen atom or the like, R3 is a hydrogen atom or the like, the ring A is C3-11 cycloalkane or the like, L1 is a C1-6 alkylene group or the like, and R4 is NRaRb or the like.