15185-66-7 Usage
Description
(2-Amino-5-chlorophenyl)-phenylmethanona E-oxium is a chemical compound that belongs to the oxime group of substances. It is a derivative of both amino and phenyl compounds, and its molecular structure includes a chlorine atom. It possesses unique reactivity and properties due to its oxime group, amino, and phenyl components, along with the presence of a chlorine atom.
Uses
Used in Organic Chemistry:
(2-Amino-5-chlorophenyl)-phenylmethanona E-oxium is used as a nucleophilic agent in various organic reactions for its ability to participate in the formation of new chemical bonds and its potential as a building block for more complex molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, (2-Amino-5-chlorophenyl)-phenylmethanona E-oxium is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a versatile component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
(2-Amino-5-chlorophenyl)-phenylmethanona E-oxium is also utilized in the agrochemical sector as a precursor for the development of pesticides and other agrochemicals. Its reactivity and structural features make it suitable for creating effective compounds for agricultural applications.
Used in Fine Chemicals Synthesis:
In the synthesis of fine chemicals, (2-Amino-5-chlorophenyl)-phenylmethanona E-oxium is used as a valuable building block. Its unique combination of functional groups and the presence of a chlorine atom contribute to the creation of specialty chemicals for various industries.
Safety Considerations:
Due to its potential reactivity and toxicological properties, (2-Amino-5-chlorophenyl)-phenylmethanona E-oxium should be handled with caution. It is essential to follow proper safety protocols during its production, use, and disposal to minimize risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 15185-66-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,8 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15185-66:
(7*1)+(6*5)+(5*1)+(4*8)+(3*5)+(2*6)+(1*6)=107
107 % 10 = 7
So 15185-66-7 is a valid CAS Registry Number.
15185-66-7Relevant articles and documents
In vivo evaluation of substituted 3-amino-1,4-benzodiazepines as anti-depressant, anxiolytic and anti-nociceptive agents
Lattmann, Eric,Lattmann, Pornthip,Boonprakob, Yodchai,Airarat, Wanchai,Singh, Harjit,Offel, Michael,Sattayasai, Jintana
scheme or table, p. 61 - 71 (2009/04/19)
Oxazepam (CAS 604-75-1) 4 a served as building block in the synthesis of substituted 3-amino-l,4-benzodiazepines, which were subsequently tested in various CNS animal models. The hydroxy group of oxazepam was either activated as a chloride (Method A) or as a phos- phor-oxy derivative (Method B) giving the desired 3-amino-l,4-benzodiapines 6 a- 6r in high yields with primary and secondary amines in a typical nucleophilic substitution reaction. Eighteen 3-substi- tuted 1,4-benzodiazepines were prepared and served as new chemical entities and for lead structure discovery. The mixed cholecystokinin (CCK) antagonist 6 e showed anxiolytic and antidepressant effects from 10μg/kg in mice in the elevated x-maze test and the forced swimming test. The CCK 1 antagonist 6 g has shown antidepressant effects from the same dose, but lacked anxiolytic properties. Both compounds potentiated at a dose of 0.5 mg/kg morphine antinocicep- tion with a maximum possible effect (MPE) about 35 %. By assessing initially the MPE of antinocipection for the 18 newly synthesised benzodiazepines in the tail-flick test, 4 other benzodiazepines were found active. In further in vivo evaluation the cyclohexyl derivative 6 i displayed anxiolytic, antidepressant and antinociceptive properties as single agent at a dose of 5 mg/kg without toxicity. The benzodiazepines 6i and 6p, which initially showed a higher MPE in terms of morphine potentiation (43/44%) showed analgesic effects as single agents, without having anxiolytic or antidepressant properties. The amino-piperidinyl derivative 6 p displayed a similar dose-response relationship to morphine, but was 3 times more potent. ECV Editio Cantor Verlag, Aulendorf (Germany).
Quinazolines and 1,4-benzodiazepines. XXVI. 1,2-Dihydroquinazoline 3-oxides.
Field,Zally,Sternbach
, p. 3957 - 3959 (2007/10/06)
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