151901-83-6

Basic information

• Product Name: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine
• Synonyms: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine
• CAS NO: 151901-83-6
• Molecular Weight: 629.709
• Mol File: 151901-83-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine(151901-83-6)
• EPA Substance Registry System: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine(151901-83-6)

Safety Data

• Hazardous Substances Data: 151901-83-6(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 73724-45-5 N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine 

Downstream Products

• 815582-34-4 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(4,4'-dimethoxytrityl)-L-serine 6-hydroxyhexylamide 

Relevant articles and documents

New method to prepare peptide-oligonucleotide conjugates through glyoxylic oxime formation

A new method to prepare peptide-oligonucleotide conjugates through chemoselective glyoxylic oxime linkage is reported. A novel phosphoramidite reagent, readily accessible from serine, was prepared and used in automated DNA synthesis to prepare oligonucleotides carrying a glyoxylic aldehyde functionality at the 5′ terminus. This was efficiently coupled to a peptide functionalized with an aminooxy group. The method could be of general use to prepare a broad range of oligonucleotide conjugates.