151928-74-4

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine
• CAS NO: 151928-74-4
• Molecular Weight: 653.692
• Mol File: 151928-74-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine(151928-74-4)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine(151928-74-4)

Safety Data

• Hazardous Substances Data: 151928-74-4(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 58-61-7 adenosine 
• 57018-82-3 5'-O-dimethoxytrityladenosine 
• 108-24-7 acetic anhydride 

Downstream Products

• 29886-19-9 2',3'-di-O-acetyladenosine 
• 1312690-35-9 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-adenosine 
• 1312690-32-6 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-2'-O-pivaloyloxymethyl-adenosine 
• 1312690-34-8 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-adenosine 
• 1312690-30-4 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine 

Relevant articles and documents

Synthesis and preliminary evaluation of pro-RNA 2′- O -masked with biolabile pivaloyloxymethyl groups in an RNA interference assay

The cellular delivery of bioactive nucleic acid-based drugs such as small interfering RNA (siRNA) represents a major technical hurdle for their pharmaceutical application. Prodrug-like approaches provide an attractive concept to address the delivery probl