15205-62-6

Basic information

• Product Name: tri-tert-butyl phosphite
• Synonyms: Phosphorous acid, tris(1,1-dimethylethyl) ester; Tri(tert-butyl) phosphite
• CAS NO: 15205-62-6
• Molecular Formula: C₁₂H₂₇O₃P
• Molecular Weight: 250.3147
• Mol File: 15205-62-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 246.9°C at 760 mmHg
• Flash Point: 122.3°C
• Vapor Pressure: 0.0415mmHg at 25°C
• CAS DataBase Reference: tri-tert-butyl phosphite(CAS DataBase Reference)
• NIST Chemistry Reference: tri-tert-butyl phosphite(15205-62-6)
• EPA Substance Registry System: tri-tert-butyl phosphite(15205-62-6)

Safety Data

• Hazardous Substances Data: 15205-62-6(Hazardous Substances Data)

Usage

Description

Tri-tert-butyl phosphite is a phosphite ester with the molecular formula C12H27O3P, consisting of a phosphorus atom bonded to three tert-butyl groups and an O-ethoxy group.

Uses

Used in Polymer and Plastic Industry:
Tri-tert-butyl phosphite is used as a stabilizer and antioxidant for polymers and plastics. It captures and neutralizes free radicals, thereby extending the longevity and structural integrity of the products.
Used in Organic Synthesis:
Tri-tert-butyl phosphite is used as a reagent in the preparation of phosphorus-containing compounds.

Upstream product

• 75-65-0 tert-butyl alcohol 

Downstream Products

• 20224-50-4 tri-(tert-butyl) phosphate 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 13086-84-5 di-tert-butyl phosphite 
• 115-11-7 isobutene 
• 873200-44-3 (dibenzylamino)methylphosphonic acid di-tert-butylester 
• 1615691-52-5 N,N-bis[2-[[[2-(1,1-dimethylethoxy)-2-oxoethyl][[bis(1,1-dimethylethoxy)phosphynyl]methyl]amino]ethyl]]-L-aspartic acid 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester 
• 345989-89-1 9-[1-[bis(1,1-dimethylethoxy)phosphinyl]-4-oxo-4-(phenylmethoxy)butyl]-6,12-bis[2-(1,1-dimethylethoxy)-2-oxoethyl]-2,2-dimethyl-4-oxo-3-oxa-6,9,12-triazatetradecan-14-oic acid 1,1-dimethylethyl ester 
• 1609936-55-1 (di-tert-butyl 2,2'-(4-(3-(benzyloxy)-2-(((benzyloxy)carbonyl)amino)-3-oxopropyl)-10-((di-tert-butoxyphosphoryl)methyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetate) 
• 808112-81-4 4-(phenylmethoxy)carbonyl-10-[[bis(1,1-dimethylethoxy)phosphinyl]methyl]-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid bis(1,1-dimethylethyl)ester 
• 321901-42-2 N-Boc-O⁴-[bi(tert-butyl)phosphoryl]-tyrosine methyl ester 
• 321901-39-7 N-Boc-O⁴-[bi(tert-butyl)phosphino]-tyrosine methyl ester 

Relevant articles and documents

Expeditious synthesis of 'P'-protected macrocycles en route to lanthanide chelate metal complexes

Phosphonic acid appended tetraazacyclododecane (cyclen)-based macrocycles are attractive metal-ion chelators for diagnostic imaging and therapeutic delivery. Here, we report a novel P-protected methodology that facilitates the rapid synthesis and purifica

Highly efficient asymmetric mannich reaction of dialkyl α-diazomethylphosphonates with N -carbamoyl imines catalyzed by chiral bronsted acids

An efficient method involving the first use of chiral phosphoric acids as catalysts in the asymmetric Mannich reaction of dialkyl diazomethylphosphonates and N-carbamoyl imines is developed. With only 0.1 mol % catalyst 1f, the reaction proceeded smoothly and produced the corresponding β-amino-α- diazophosphonate with up to 97% yield and >99% ee.

Syntheses und NMR-Spektren phosphororganischer Antioxidantien und verwandter Verbindungen

The syntheses of various aliphatic, aromatic, sterically hindered, and cyclic organophosphorus compounds (phosphorous acid esters, esters chlorides and ester amides, hydrogen phosphites, phosphinates and phosphates) are reported, and general procedures for preparation are given.The compounds synthesized were investigated by means of 31P-, 1H- and 13C-n.m.r. spectroscopy, and the chemical shifts measured are listed.