152065-57-1

Basic information

• Product Name: 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether
• Synonyms: 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether
• CAS NO: 152065-57-1
• Molecular Weight: 552.706
• Mol File: 152065-57-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether(152065-57-1)
• EPA Substance Registry System: 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether(152065-57-1)

Safety Data

• Hazardous Substances Data: 152065-57-1(Hazardous Substances Data)

Upstream product

• 2162-31-4 2-(tetrahydropyran-2-yloxy)ethanol 
• 18226-42-1 1,3,5-Tris(bromomethyl)benzene 
• 2672-58-4 1,3,5-tris-(methoxycarbonyl)benzene 
• 554-95-0 benzene-1,3,5-tricarboxylic acid 
• 17739-45-6 2-(2-bromoethoxy)tetrahydropyran 
• 4464-18-0 1,3,5-tris(hydroxymethyl)benzene 

Downstream Products

• 152065-65-1 1,3,5-tris[4'-(tosyloxy)-2'-oxa-1'-butyl]benzene 
• 864383-28-8 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene 
• 864383-25-5 1,3,5-tris-((2'-methylmalonyl)ethoxymethyl)benzene 
• 152065-61-7 1,3,5-tris-((2'-hydroxy)ethoxymethyl)benzene 

Relevant articles and documents

Synthesis and orthogonal functionalization of [60]fullerene e,e,e-trisadducts with two spherically defined addend zones

e,e,e-Trisadducts 13 and 15 have been prepared by a highly regioselective threefold cyclopropanation of tripodal malonates 10 and 12 with C60. The yield and regioselectivity depend on the length and structure of the tethers that connect the malonate units to the focal benzene core of 13-15. As a consequence of the template-directed synthesis, all ce.e-trisadducts were formed as in/out isomers exclusively and contain two spherically well-defined addend zones with equatorial and polar orientation, respectively. By variation of the outer malonate termini of the tethers, selective functionalization of the equatorial addend zone could be achieved, thus leading to fine-tuning of intermolecular interactions, such as solubility or aggregation phenomena. After removal of the focal benzene moiety in 14 and 15, selective functionalization of the polar addend zone could be achieved. Strong intramolecular hydrogen-bonding networks of the polar substituents in the polar addend zone could be observed by 1H NMR spectroscopic analysis. By orthogonal functionalization of both addend zones, fullerene derivatives 44-48 could be synthesized as one single in/out isomer, thus greatly enhancing the potential of e,e,e-trisadducts as building blocks in supramolecular architectures.

Regioselective synthesis and zone selective deprotection of [60]fullerene tris-adducts with an e,e,e addition pattern

D3h-symmetrical tripodal tris(malonate) tethers have been used for the synthesis of [60]fullerene tris-adducts with an e,e,e addition pattern bearing topologically distinct polar and equatorial addend zones that can selectively be deprotected. The Royal Society of Chemistry 2005.