15210-64-7 Usage
Description
N-acetyl-3,5,7-trimethyl-1-aminoadamantane, also known as 7-Acetamido-1,3,5-trimethyladamantane, is an organic compound that serves as a crucial intermediate in the synthesis of related compounds of Memantine. It is characterized by its adamantane core structure, which is a bicyclic structure consisting of two fused cyclohexane rings, and its acetyl and trimethyl groups attached to specific carbon atoms.
Uses
Used in Pharmaceutical Industry:
N-acetyl-3,5,7-trimethyl-1-aminoadamantane is used as an intermediate in the synthesis of Memantine (HCl salt, M218000) for its antiparkinsonian and antispasmodic properties. Memantine is a medication primarily used to treat Parkinson's disease and various spastic conditions by acting on the central nervous system and providing relief from symptoms.
In the synthesis process, N-acetyl-3,5,7-trimethyl-1-aminoadamantane plays a vital role in the formation of Memantine, which is the active pharmaceutical ingredient in the final drug product. The compound's unique structure and properties make it an essential component in the development of medications targeting neurological disorders and muscle spasms.
Check Digit Verification of cas no
The CAS Registry Mumber 15210-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,1 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15210-64:
(7*1)+(6*5)+(5*2)+(4*1)+(3*0)+(2*6)+(1*4)=67
67 % 10 = 7
So 15210-64-7 is a valid CAS Registry Number.
15210-64-7Relevant articles and documents
Kovacic,Roskos
, p. 6457 (1969)
Jones,S.R.,Mellor,J.M.
, p. 385 - 386 (1976)
Synthesis of Cage Acylamino Derivatives in Nitric Acid Medium
Klimochkin, Yu. N.,Leonova,Ivleva,Kazakova,Zaborskaya
, (2021/03/04)
Abstract: An efficient procedure has been developed for the synthesis of secondary amides by the Ritter reaction of cage substrates with a wide series of nitriles in fuming nitric acid and its mixtures.
ADAMANTANOL NITRATES IN NUCLEOPHILIC SUBSTITUTION REACTIONS
Moiseev, I. K.,Bagrii, E. I.,Klimochkin, Yu. N.,Dolgopolova, T. N.,Zemtsova, M. N.,Trakhtenberg, P. L.
, p. 1983 - 1985 (2007/10/02)
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