1522415-30-0

Basic information

• Product Name: diethyl (3,5-dibromo-4-hydroxyphenylamino)(2,4-dimethoxyphenyl)methylphosphonate
• Synonyms: diethyl (3,5-dibromo-4-hydroxyphenylamino)(2,4-dimethoxyphenyl)methylphosphonate
• CAS NO: 1522415-30-0
• Molecular Weight: 553.184
• Mol File: 1522415-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl (3,5-dibromo-4-hydroxyphenylamino)(2,4-dimethoxyphenyl)methylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (3,5-dibromo-4-hydroxyphenylamino)(2,4-dimethoxyphenyl)methylphosphonate(1522415-30-0)
• EPA Substance Registry System: diethyl (3,5-dibromo-4-hydroxyphenylamino)(2,4-dimethoxyphenyl)methylphosphonate(1522415-30-0)

Safety Data

• Hazardous Substances Data: 1522415-30-0(Hazardous Substances Data)

Upstream product

• 609-21-2 2,6-dibromo-4-aminophenol 
• 762-04-9 phosphonic acid diethyl ester 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Relevant articles and documents

CeCl 3·7H 2O Catalyzed, microwave-assisted high-yield synthesis of α-aminophosphonates and their biological studies

A new class of diethyl(3,5-dibromo-4-hydroxyphenylamino) (substituted phenyl/heterocyclic) methylphosphonates 4(a-j) has been synthesized by one-pot three component simultaneous reaction (Kabachnik-Fields) of 4-amino-2,6- dibromophenol 1, substituted heterocyclic/phenyl aldehydes 2(a-j), and diethylphosphite 3 using a Lewis acid catalyst, CeCl3·7H2O (5 mol%) under microwave irradiation as well as conventional conditions. It was observed that microwave irradiation method is more facile, efficient, and advantageous with respect to reaction time and yields. The structures of all the synthesized compounds were supported by analyzing IR, 1H/13C/ 31P NMR, and mass spectral data. The synthesized compounds were screened for their in vitro antimicrobial and antioxidant activities.