15256-81-2

Basic information

• Product Name: (E)-1-(1,1,1-trifluorohex-2-en-2-yl)benzene
• CAS NO: 15256-81-2
• Molecular Weight: 214.23
• Mol File: 15256-81-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(1,1,1-trifluorohex-2-en-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(1,1,1-trifluorohex-2-en-2-yl)benzene(15256-81-2)
• EPA Substance Registry System: (E)-1-(1,1,1-trifluorohex-2-en-2-yl)benzene(15256-81-2)

Safety Data

• Hazardous Substances Data: 15256-81-2(Hazardous Substances Data)

Upstream product

• 998-40-3 tributylphosphine 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 1779-51-7 n-butyl(triphenyl)phosphonium bromide 

Relevant articles and documents

Highly selective iridium-catalyzed asymmetric hydrogenation of trifluoromethyl olefins: A new route to trifluoromethyl-bearing stereocenters

Fluorine-containing compounds are useful in many applications ranging from pharmaceuticals to ferroelectric crystals. We have developed a new, highly enantioselective synthetic route to trifluoromethyl-bearing stereocenters in up to 96% ee via asymmetric hydrogenation using N,P-ligated iridium catalysts. We also hydrogenated an isomeric mixture of olefins; this reaction gave the hydrogenation product highly enantioselectively (87% ee), and only the E isomer was present after the reaction had reached 56% conversion.