152580-30-8

Basic information

• Product Name: 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI)
• Synonyms: 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI);(4S)-4-aminodihydro-2(3H)-Furanone;S-2(3H)-Furanone, 4-aminodihydro-
• CAS NO: 152580-30-8
• Molecular Formula: C4H7NO2
• Molecular Weight: 101.1
• Product Categories: VARIOUSAMINE
• Mol File: 152580-30-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 257.1±33.0 °C(Predicted)
• Appearance: /
• Density: 1.206±0.06 g/cm3(Predicted)
• PKA: 6.38±0.20(Predicted)
• CAS DataBase Reference: 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI)(152580-30-8)
• EPA Substance Registry System: 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI)(152580-30-8)

Safety Data

• Hazardous Substances Data: 152580-30-8(Hazardous Substances Data)

Usage

General Description

2(3H)-Furanone,4-aminodihydro-,(S)-(9CI) is a chemical compound with the molecular formula C4H7NO2. It is also known as (S)-4-amino-2,5-dihydro-2(3H)-furanone. 2(3H)-Furanone,4-aminodihydro-,(S)-(9CI) is a chiral molecule, meaning it has a non-superimposable mirror image. It is commonly used in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and functional groups. The compound is also known for its pleasant aroma and is often used in the production of fragrances and flavors. Additionally, it has been studied for its potential biological activities, including antimicrobial and antitumor properties.

Upstream product

• 87219-29-2 benzyl (3S)-5-oxotetrahydro-3-furanylcarbamate 
• 118399-28-3 (R)-4-benzyloxycarbonylamino-4,5-dihydro-2(3H)-furanone 
• 98063-21-9 Emeriamine 
• 127560-92-3 (R,S)-4-benzylamino-4,5-dihydro-2(3H)-furanone 

Downstream Products

• 1421583-00-7 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(3S)-5-oxotetrahydrofuran-3-yl]benzamide 

Relevant articles and documents

Kras inhibitory cyclic peptide compound

The following were discovered: a cyclic peptide compound that interacts with Ras; and an unnatural amino acid that is useful in the production of said cyclic peptide compound. The cyclic peptide compound was also discovered to inhibit bonding between Ras and SOS. The following were additionally discovered: a specific unnatural amino acid included in said cyclic peptide compound; and a manufacturing method therefor.

N-substituted 4-amino-3,3-dipropyl-2(3H)-furanones: New positive allosteric modulators of the GABAA receptor sharing electrophysiological properties with the anticonvulsant loreclezole

1,4-Addition of benzylamine to 2(5H)-furanone followed by dialkylation of the 3-position with allylbromide gave (±)-4-benzyl-3,3-diallyl-2(3H)-furanone (8), which served as the intermediate for the synthesis of various N-substituted 4-amino-3,3-dipropyl-2