152749-21-8Relevant articles and documents
Nitro compounds, process for preparation thereof and use thereof
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, (2008/06/13)
A new nitro compound of the formula: STR1 wherein R1 and R2 are each lower alkyl or lower alkoxy(lower)alkyl, or STR2 is cyclized to form STR3 X is --O--, --S-- or --NH--, m is an integer 0 or 1, and R3 is carbamoyl, lower alkylcarbamoyl, lower alkanoyl, di-lower alkylaminosulfonyl, lower alkylsulfonyl, oxamoyl or a group of the formula: --(Y)n --R4 wherein Y is --CO--, --SO2 --, --COCH2 -- or STR4 n is an integer of 0 or 1, and R4 is heterocyclic group which is optionally substituted with one or more substituents selected from lower alkyl, lower alkoxy, phenyl, carbamoyl, halogen, amino, lower alkylthio, hydroxy, lower alkylsulfonylamino and carbamoylmethyl, and pharmaceutically acceptable salt thereof, which are useful as vasodilators.