152857-74-4

Basic information

• Product Name: (R)-(+)-[1-Benzyl-3-(N,N-dibenzylamino)-propyl] 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate
• CAS NO: 152857-74-4
• Molecular Weight: 500.681
• Mol File: 152857-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(+)-[1-Benzyl-3-(N,N-dibenzylamino)-propyl] 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-[1-Benzyl-3-(N,N-dibenzylamino)-propyl] 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate(152857-74-4)
• EPA Substance Registry System: (R)-(+)-[1-Benzyl-3-(N,N-dibenzylamino)-propyl] 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate(152857-74-4)

Safety Data

• Hazardous Substances Data: 152857-74-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 90-39-1 (-)-sparteine 

Relevant articles and documents

Preparation of sec. or tert. alcohols

A process for the preparation of a compound of the formula STR1 which comprises deprotonating a carbamate of the formula STR2 in an inert solvent with a selective base, in the presence of a chelate-forming diamine to give a compound of the formula STR3 and then reacting III in an inert solvent, either with an achiral electrophile of the formula (IV) or (V) or with an optionally prochiral electrophile of the formula (VI) STR4 and in the case in which R1 represents an electrofugic leaving group, optionally again electrophilically substituted with the formation of an acyl anion and renewed deprotonation, and in a last step, solvolytically removing the protecting group --CO--NR10 R11.