152897-52-4Relevant articles and documents
Ring opening of optically active cis-disubstituted aziridino alcohols: An enantiodivergent synthesis of functionalized amino alcohol derivatives
Fuji, Kaoru,Kawabata, Takeo,Kiryu, Yoshimitsu,Sugiura, Yukio
, p. 701 - 722 (2007/10/03)
Ring-opening reactions of optically active cis-disubstituted aziridino alcohols have been investigated. Regio- and stereo-selective ring opening took place with internal and external nucleophiles. Unusual amino acids derivatives (14) and (15), the key synthetic intermediates for bestatin and related peptides, have been prepared. n.