15308-34-6

Basic information

• Product Name: Norfenefrine hydrochloride
• Synonyms: alpha-(aminomethyl)-3-hydroxy-,hydrochloride,(+-)-benzenemethano;alpha-(aminomethyl)-m-hydroxy-,hydrochloride,(+-)-benzylalcoho;dl-m-octopaminehydrochloride;novadral;zondel;NORFENEFRINE HYDROCHLORIDE;(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE;NORPHENYLEPHRINE HYDROCHLORIDE
• CAS NO: 15308-34-6
• Molecular Formula: C₈H₁₁NO₂*ClH
• Molecular Weight: 189.64
• EINECS: 239-351-1
• Mol File: 15308-34-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 162-164 °C(lit.)
• Appearance: /
• Merck: 6699
• CAS DataBase Reference: Norfenefrine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Norfenefrine hydrochloride(15308-34-6)
• EPA Substance Registry System: Norfenefrine hydrochloride(15308-34-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 22-26
• WGK Germany: 3
• RTECS: DN7400000
• HazardClass: IRRITANT
• Hazardous Substances Data: 15308-34-6(Hazardous Substances Data)

Usage

Safety Profile

Poison by ingestion,subcutaneous, intravenous and intraperitoneal routes.When heated to decomposition it emits toxic fumes ofNOx and HCl.

InChI:InChI=1/C8H11NO2.ClH/c9-4-7-6(5-10)2-1-3-8(7)11;/h1-3,10-11H,4-5,9H2;1H

Upstream product

• 4779-94-6 (+/-)-norphenylephrine hydrochloride 

Relevant articles and documents

The Resolution and Absolute Configuration by X-Ray Crystallography of the Isomeric Octopamines and Synephrines

Racemates of the naturally occuring biogenic amines, o-, m-, and p-octopamine and p-synephrine, have been resolved by the preparation of suitable diastereomeric salts with antipodes of appropriate organic acids.The circular dichroism (c.d.) curves of (-)-m-octopamine hydrochloride and (-)-m-synephrine hydrochloride were superimposable and of opposite sign to those of the corresponding (-)-p-derivatives.X-ray crystallography of the (-)-3-bromocamphor-8-sulphonate salt of (-)-p-synephrine confirmed (for the first time by direct means in this series of compounds) that the absolute configuration of (-)-p-synephrine is R.It is concluded from the c.d. data that the absolute configuration of (-)-p-octopamine is also R.