1531585-31-5

Basic information

• Product Name: (4R,5R)-5-(((2S,5S)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)methyl)-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one
• Synonyms: (4R,5R)-5-(((2S,5S)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)methyl)-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one
• CAS NO: 1531585-31-5
• Molecular Weight: 334.412
• Mol File: 1531585-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5R)-5-(((2S,5S)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)methyl)-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-5-(((2S,5S)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)methyl)-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one(1531585-31-5)
• EPA Substance Registry System: (4R,5R)-5-(((2S,5S)-5-((benzyloxy)methyl)tetrahydrofuran-2-yl)methyl)-4-hydroxy-3,3-dimethyldihydrofuran-2(3H)-one(1531585-31-5)

Safety Data

• Hazardous Substances Data: 1531585-31-5(Hazardous Substances Data)

Upstream product

• 571167-73-2 (2S)-tetrahydro-5-hydroxy-2-(benzyloxymethyl)furan 
• 155418-40-9 (2S)-1-(benzyloxy)hex-5-en-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 100-39-0 benzyl bromide 

Downstream Products

• 1531585-34-8 (2R,3a′R,5S,6a′R)-5-((benzyloxy)methyl)-6′,6′-dimethyltetrahydro-3H,3′H-spiro[furan-2,2′-furo[3,2-b]furan]-5′(3a′H)-one 
• 1531585-35-9 (2S,3a′R,5S,6a′R)-5-((benzyloxy)methyl)-6′,6′-dimethyltetrahydro-3H,3′H-spiro[furan-2,2′-furo[3,2-b]furan]-5′(3a′H)-one 

Relevant articles and documents

Synthesis of the spiroacetal core of the cephalosporolide family of natural products

The synthesis of four possible stereoisomers of the spiroacetal core of the natural products cephalosporolides H and I and penisporolides A and B is described. The key steps involve the use of Sharpless asymmetric dihydroxylation to install the desired stereochemistry of the γ-lactone ring and an oxidative radical cyclisation to form the spiroacetal ring system.