153208-22-1Relevant articles and documents
Design and Synthesis of Fused Pyridine Building Blocks for Automated Library Generation
Mora-Radó, Helena,Czechtizky, Werngard,Méndez, María,Harrity, Joseph P. A.
, p. 328 - 334 (2021)
We demonstrate that a diboration-electrocyclization sequence provides access to a range of pyridine-fused, small-molecule boronic ester building blocks, and that these are amenable to high-throughput synthesis leading to biaryl and ether-linked compound libraries. Moreover, the implementation of an integrated physicochemical and ADME profiling workflow allows accelerated design of novel lead compounds for application in drug-discovery projects.
Pyrazoles, fungicidal compositions and use
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, (2008/06/13)
The invention compounds of formula I STR1 wherein R is H, C1-4 alkyl; optionally substituted aryl or CF3 ; Y is C1-4 alkyl or optionally substituted aryl; A is nitrogen or CH; and Z is optionally substituted hydrocarbyl or