153209-97-3

Basic information

• Product Name: 3-OXETANEMETHANAMINE, 3-METHYL-
• Synonyms: 3-OXETANEMETHANAMINE, 3-METHYL-;3-Aminomethyl-3-methyl-oxetane;(3-methyloxetan-3-yl)methanamine;1-(3-methyloxetan-3-yl)methanamine;C-(3-Methyl-oxetan-3-yl)-methylamine;3-Aminomethyl-3-methyl-ox...;1-(3-methyloxetan-3-yl)methanamine(SALTDATA: FREE);3-Methyl-3-oxetanemethanamine
• CAS NO: 153209-97-3
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.14694
• Mol File: 153209-97-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 134.5±13.0℃ (760 Torr)
• Flash Point: 35.5±13.1℃
• Appearance: /
• Density: 0.961±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 8.076mmHg at 25°C
• Refractive Index: 1.45
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.65±0.29(Predicted)
• CAS DataBase Reference: 3-OXETANEMETHANAMINE, 3-METHYL-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXETANEMETHANAMINE, 3-METHYL-(153209-97-3)
• EPA Substance Registry System: 3-OXETANEMETHANAMINE, 3-METHYL-(153209-97-3)

Safety Data

• Hazard Codes: Xn
• Statements: 10-22
• RIDADR: UN1993
• HazardClass: IRRITANT
• Hazardous Substances Data: 153209-97-3(Hazardous Substances Data)

Usage

General Description

3-Oxetanemethanamine, 3-methyl- is a chemical compound that is also known as 3-methyl-3-aminooxetane. It is a clear, colorless liquid with a low boiling point and is highly flammable. 3-OXETANEMETHANAMINE, 3-METHYL- is used in the production of pharmaceuticals and as a building block for the synthesis of various other chemical compounds. It is also used as an intermediate in the creation of agrochemicals, fragrances, and other specialty chemicals. Additionally, 3-Oxetanemethanamine, 3-methyl- has potential uses in the production of advanced materials and in research and development for various industries. However, it is important to handle this chemical with caution due to its flammability and potential health hazards.

InChI:InChI=1/C5H11NO/c1-5(2-6)3-7-4-5/h2-4,6H2,1H3

Upstream product

• 3864-43-5 methanesulfonic acid 3-methyloxetan-3-ylmethyl ester 
• 3143-02-0 3-hydroxymethyl-3-methyloxethane 
• 90683-29-7 3-(azidomethyl)-3-methyloxetane 
• 77-85-0 2-(hydroxymethyl)-2-methylpropane-1,3-diol 
• 153004-74-1 2-(3-methyloxetan-3-ylmethyl)isoindol-1,3-dione 

Downstream Products

• 202871-66-7 N-(3-Methyl-oxetan-3-ylmethyl)-butyramide 
• 202871-67-8 N-(3-Methyl-oxetan-3-ylmethyl)-2-phenyl-acetamide 
• 202871-63-4 N-(3-Methyl-oxetan-3-ylmethyl)-benzamide 
• 1428631-20-2 5-((3-fluorophenyl)ethynyl)-N-((3-methyloxetan-3-yl)-methyl)picolinamide 

Relevant articles and documents

ORGANIC COMPOUNDS

Disclosed are δ-amino-γ-hydroxy-ω-aryl-alkanoic acid amide compounds of formula (I)and the salts thereof, having renin-inhibiting properties. Also disclosed are pharmaceutical compositions comprising these compounds and methods of administering them for the treatment of hypertension, atherosclerosis, unstable coronary syndrome, congestive heart failure, cardiac hypertrophy, cardiac fibrosis, cardiomyopathy postinfarction, unstable coronary syndrome, diastolic dysfunction, chronic kidney disease, hepatic fibrosis, complications resulting from diabetes, such as nephropathy, vasculopathy and neuropathy, diseases of the coronary vessels, restenosis following angioplasty, raised intra-ocular pressure, glaucoma, abnormal vascular growth, hyperaldosteronism, cognitive impairment, alzheimers, dementia, anxiety states and cognitive disorders.

Double Isomerization of Oxetane Amides to Azetidine Esters with Ring Expansion and Contraction

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Chemoselective isomerization of amide-substituted oxetanes with Lewis acid to give oxazine derivatives or bicyclic amide acetals

The Lewis-acid catalyzed isomerization of secondary and tertiary amide-substituted oxetanes takes place chemoselectively, giving 5-hydroxymethyl-5,6-dihydro-4H-1,3-oxazines and reactive amide acetals consisting of a bicyclo[2.2.2]octane skeleton, respectively.