153233-91-1

Basic information

• Product Name: ETOXAZOLE
• Synonyms: ETOXAZOLE;Oxazole, 2-(2,6-difluorophenyl)-4-4-(1,1-dimethylethyl)-2-ethoxyphenyl-4,5-dihydro-;etoxazole (bsi, pa iso);yi-5301;2-(2,6-Difluorophenyl)-4-(4-(1,1-dimethylethyl)-2-ethoxyphenyl)-4,5-di hydrooxazole;ETOXAZOLE STANDARD;etoxazol;2-(2,6-Difluorophenyl)-4-[4-(tert-butyl)-2-ethoxyphenyl]-4,5-dihydrooxazole
• CAS NO: 153233-91-1
• Molecular Formula: C21H23F2NO2
• Molecular Weight: 359.41
• EINECS: 201-167-4
• Mol File: 153233-91-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 101-102°
• Boiling Point: 449.1 °C at 760 mmHg
• Flash Point: 457℃
• Appearance: /
• Density: 1.15 g/cm³
• Vapor Pressure: 7.78E-08mmHg at 25°C
• Refractive Index: 1.537
• Storage Temp.: 0-6°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 2.04±0.70(Predicted)
• Stability: Hygroscopic
• BRN: 8930214
• CAS DataBase Reference: ETOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: ETOXAZOLE(153233-91-1)
• EPA Substance Registry System: ETOXAZOLE(153233-91-1)

Safety Data

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: RP6795100
• Hazardous Substances Data: 153233-91-1(Hazardous Substances Data)

Usage

Description

Etoxazole is an organofluorine acaricide, characterized by its pale-yellow liquid appearance when pure and a reddish-brown liquid or semisolid form as a technical product with a mild odor. It is known for its toxicity in two-spotted spider mite (T. urticae) larvae and its ability to induce a concentration-dependent reduction in acetylcholinesterase (AChE) activity in the freshwater fish O. niloticus. Additionally, etoxazole has been shown to inhibit the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner.

Uses

Used in Agriculture:
Etoxazole is used as an acaricide/insecticide for the control of mites, specifically through the inhibition of chitin biosynthesis. This makes it a valuable tool in agricultural settings for managing mite infestations and protecting crops.
Used in Pesticide Detection:
Isotope-labelled Etoxazole serves as a standard for pesticide detection, making it an essential component in the development and calibration of analytical methods for pesticide residue monitoring.
Used in Cannabis Testing Kits:
Etoxazole is also utilized as a component of pesticide mixes in cannabis testing kits (P698235), ensuring the quality and safety of cannabis products by detecting the presence of harmful pesticide residues.

Potential Exposure

Aromatic hydrocarbon; Thiazole fungicide Etridiazole is a fungicide used in some countries as a seed treatment on barley, beans, corn, cotton, peanuts, peas, sorghum, soybeans, safflower, and wheat. It is also used on cotton for in-furrow application at planting, on ornamental plants and shrubs by horticultural nurseries, on nonbearing citrus and nonbearing coffee, and for golf course fairways, tees and greens. Some states hold Special Local Need registrations for use on tobacco transplants

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.

Incompatibilities

Diazo compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. This chemical is sensitive to prolonged exposure to heat. This chemical is incompatible with strong oxidizing agents

Waste Disposal

Incineration would be an effective disposal procedure where permitted. If an efficient incinerator is not available, the product should be mixed with large amounts of combustible material and contact with the smoke should be avoided. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers

InChI:InChI=1/C21H23F2NO2/c1-5-25-18-11-13(21(2,3)4)9-10-14(18)17-12-26-20(24-17)19-15(22)7-6-8-16(19)23/h6-11,17H,5,12H2,1-4H3

Relevant articles and documents

Etoxazole preparation method

The invention provides an etoxazole preparation method. The etoxazole preparation method comprises the step: enabling a compound as shown in a formula I to react with ammonia gas or an ammonium solution, thus generating etoxazole. The preparation method p

2-(2,6-difluorophenyl)-4-(2-ethoxy-4-tert-butylphenyl)-2-oxazoline

2-(2,6-difluorophenyl)-4-(2-ethoxy-4-tert-butylphenyl)-2-oxazoline. This compound is useful as miticide.