153652-70-1 Usage
General Description
"(4S,5R)-3-Benzoyl-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid" is a complex organic compound with multiple functional groups. The name suggests its structure and stereochemistry. "4S,5R" indicates its stereocenters, two chiral carbon atoms located at the 4th and 5th positions, with the "S" and "R" representing the specific configuration of these atoms. The compound has a benzoyl group (aromatic ring of benzene attached to a carbonyl group) at the 3rd position. The "dimethyl" part indicates two methyl groups (CH3) attached to the same carbon atom. The "phenyl" suggests another aromatic ring of benzene, and "oxazolidine" refers to a five-membered heterocyclic ring containing oxygen and nitrogen. Lastly, the mention of "carboxylic acid" indicates the presence of a carboxylic acid functional group (-COOH). (4S,5R)-3-Benzoyl-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid can potentially be used in a variety of chemical reactions given its complex structure, with the specifics depending on the chemical context.
Check Digit Verification of cas no
The CAS Registry Mumber 153652-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,6,5 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 153652-70:
(8*1)+(7*5)+(6*3)+(5*6)+(4*5)+(3*2)+(2*7)+(1*0)=131
131 % 10 = 1
So 153652-70-1 is a valid CAS Registry Number.
InChI:InChI=1/C19H19NO4/c1-19(2)20(17(21)14-11-7-4-8-12-14)15(16(24-19)18(22)23)13-9-5-3-6-10-13/h3-12,15-16H,1-2H3,(H,22,23)/t15-,16+/m0/s1
153652-70-1Relevant articles and documents
Asymmetric epoxidation of cis-alkenes with arabinose-derived ketones: enantioselective synthesis of the side chain of Taxol
Shing, Tony K.M.,Luk, To,Lee, Chi M.
, p. 6621 - 6629 (2007/10/03)
The ee values of asymmetric epoxidation of cis-ethyl cinnamate 15 with arabinose-derived ketones as catalyst and Oxone as the terminal oxidant were found to increase inversely with the size of the catalyst acetal blocking group. Ketone catalyst
Methods for the preparation of taxanes using oxazolidine intermediates
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Example 6, (2008/06/13)
Novel oxazolidines finding utility as intermediates in the preparation of C-13 acyloxy sidechain-bearing taxanes such as paclitaxel and analogs thereof. The present invention also relates to novel methods of coupling the oxazolidines to form the aforementioned taxanes, and to methods of preparing the oxazolidines.
Total asymmetric synthesis of taxol by dehydration condensation between 7-TES baccatin III and protected N-benzoylphenylisoserines prepared by enantioselective aldol reaction
Shiina, Isamu,Saitoh, Katsuyuki,Frechard-Ortuno, Isabelle,Mukaiyama, Teruaki
, p. 3 - 4 (2007/10/03)
Total asymmetric synthesis of Taxol was completed by dehydration condensation between a protected N-benzoylphenylisoserine 4 or 9 and 7-TES baccatin in which was prepared from 8-membered ring enone. Taxol side chains 4, 7, 9 and 11, optically active protected N-benzoylphenylisoserines, were successfully synthesized by enantioselective aldol reaction from two achiral starting materials, benzaldehyde and an enol silyl ether derived from S-ethyl benzyloxyethanethioate.
