1537171-88-2

Basic information

• Product Name: 1-(1,1-difluoroallyl)-3,5-dimethoxybenzene
• CAS NO: 1537171-88-2
• Molecular Weight: 214.212
• Mol File: 1537171-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1,1-difluoroallyl)-3,5-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,1-difluoroallyl)-3,5-dimethoxybenzene(1537171-88-2)
• EPA Substance Registry System: 1-(1,1-difluoroallyl)-3,5-dimethoxybenzene(1537171-88-2)

Safety Data

• Hazardous Substances Data: 1537171-88-2(Hazardous Substances Data)

Upstream product

• 420-90-6 3-bromo-3,3-difluropropene 
• 192182-54-0 3,5-dimethoxyphenylboronic acid 

Relevant articles and documents

Highly selective gem -difluoroallylation of organoborons with bromodifluoromethylated alkenes catalyzed by palladium

A first example of Pd-catalyzed gem-difluoroallylation of organoborons using 3-bromo-3,3-difluoropropene (BDFP) in high efficiency with high α/γ-substitution regioselectivity has been developed. The reaction can also be extended to substituted BDFPs and has advantages of low catalyst loading (0.8 to 0.01 mol %), broad substrate scope, and excellent functional group compatibility, thus providing a facile route for practical application in drug discovery and development.