153749-96-3

Basic information

• Product Name: N-benzyl-N-boc-β-alanine ethyl ester
• Synonyms: N-benzyl-N-boc-β-alanine ethyl ester
• CAS NO: 153749-96-3
• Molecular Weight: 307.39
• Mol File: 153749-96-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-boc-β-alanine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-boc-β-alanine ethyl ester(153749-96-3)
• EPA Substance Registry System: N-benzyl-N-boc-β-alanine ethyl ester(153749-96-3)

Safety Data

• Hazardous Substances Data: 153749-96-3(Hazardous Substances Data)

Upstream product

• 140-88-5 ethyl acrylate 
• 100-46-9 benzylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 23583-21-3 ethyl-3-benzylamino propionate 
• 42201-84-3 1-ethoxy-1-(tert-butyldimethylsilyloxy)ethene 

Downstream Products

• 877998-33-9 4-(N-benzyl-N-tert-butoxycarbonylamino)-2-methylbutan-2-ol 
• 289889-03-8 3-N-[N(tert-butyloxycarbonyl)benzylamino]-propanoic acid 
• 185740-85-6 (E)-6-[Benzyl-(4-trimethylsilanyl-but-2-ynyl)-amino]-hex-3-en-2-one 
• 185740-86-7 4-acetonyl-1-benzyl-3-vinylidenepiperidine 
• 169129-44-6 (E)-6-[N-benzyl-N-(tert-butoxycarbonyl)amino]-3-hexen-2-one 
• 98014-77-8 3-(N-benzyl-N-tert-butoxycarbonylamino)propanal 
• 98014-76-7 3-[N-benzyl-N-(tert-butoxycarbonyl)amino]propan-1-ol 

Relevant articles and documents

METHOD FOR PRODUCING L-CARNOSINE DERIVATIVE AND ITS SALT

PROBLEM TO BE SOLVED: To provide a method for producing an L-carnosine derivative or its salt by a safe and simple method. SOLUTION: There is provided a method for producing an L-carnosine derivative or its salt from N-substituted benzyl-carboxylic anhydride by performing a desubstitution benzyl reaction and as necessary, a de-esterification reaction, which comprises a step of reacting N-substituted benzyl-carboxylic anhydride and a histidine compound or its salt in the presence of a base, followed performing at least a decarboxylation reaction by converting the inside of the reaction system into an acidic atmosphere to produce an N-substituted benzyl-L-carnosine derivative represented by the formula (3). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

COMPOUNDS HAVING β2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY

This invention provides compounds of formula I wherein R1, R2, R3, R4, R5, R6, R7, R8a, R8b, W, a and b are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.

Oxidative Generation of N-Acyliminium Ions from N-1-(Tributylstannyl)alkyl Carboxamides and Carbamates and Their Reactions with Carbon Nucleophiles

Oxidation of N-1-(tributylstannyl)alkyl carboxamides and carbamates with ammonium hexanitratocerate (IV) or ferrocenium hexafluorophosphate generates their N-acyliminium ions by the elimination of tributylstannyl radical under mild reaction conditions.The