1538-72-3Relevant articles and documents
P-Toluenesulfonic acid-Celite as a reagent for synthesis of esters of alkylphosphonic acids under solvent-free conditions
Gupta, Arvind K.,Kumar, Rajesh,Dubey, Devendra K.,Kaushik
, p. 328 - 331 (2008/02/10)
The coupling reaction of alkylphosphonic acids and alcohols on the surface of p-toluenesulfonic acid-Celite under mild and solvent-free conditions gave the corresponding phosphonates in excellent yields. This method provides a useful rapid synthesis of phosphonates for use in the unambiguous identification of chemical warfare agents.
Mild and efficient Cs2CO3-promoted synthesis of phosphonates
Cohen, Richard J.,Fox, Daniel L.,Eubank, Jarrod F.,Salvatore, Ralph Nicholas
, p. 8617 - 8621 (2007/10/03)
A mild and convenient synthesis for phosphonates using cesium carbonate (Cs2CO3), tetrabutylammonium iodide (TBAI) and DMF was developed at room temperature. Numerous dialkyl phosphites were screened using a diverse array of alkyl halides and these reaction conditions were found to be highly efficient producing various phosphonates exclusively in moderate to high yields.
