153809-46-2

Basic information

• Product Name: (S)-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-hydroxy-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
• Synonyms: (S)-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-hydroxy-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
• CAS NO: 153809-46-2
• Molecular Weight: 420.665
• Mol File: 153809-46-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-hydroxy-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-hydroxy-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(153809-46-2)
• EPA Substance Registry System: (S)-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-hydroxy-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(153809-46-2)

Safety Data

• Hazardous Substances Data: 153809-46-2(Hazardous Substances Data)

Upstream product

• 18052-27-2 tert-butyldimethyl(phenoxy)silane 
• 104264-93-9 (1R,2S,5R)-2-tert-butyl-5-metylcyclohexyl glyoxylate 

Downstream Products

• 13244-75-2 (S)-α,4-dihydroxy-benzeneacetic acid 

Relevant articles and documents

Synthesis of optically active 4-hydroxymandelic acid and derivatives via regio- and stereoselective Friedel-Crafts alkylation

Optically active 4-hydroxymandelic esters were prepared in good yields and very high diastereoselectivity (up to 96% d.e.) via para-hydroxyalkylation of phenolic ethers. Enantiomeric pure 4-hydroxymandelic acid is available by hydrolysis.