153833-78-4

Basic information

• Product Name: 1-(2-Fluorophenyl)-3-methyl-4,5-2H-1,2,4-triazol-one
• Synonyms: 3H-1,2,4-Triazol-3-one, 2-(2-fluorophenyl)-1,2-dihydro-5-methyl-
• CAS NO: 153833-78-4
• Molecular Formula: C₉H₈FN₃O
• Molecular Weight: 193.2
• Mol File: 153833-78-4.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: 1-(2-Fluorophenyl)-3-methyl-4,5-2H-1,2,4-triazol-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Fluorophenyl)-3-methyl-4,5-2H-1,2,4-triazol-one(153833-78-4)
• EPA Substance Registry System: 1-(2-Fluorophenyl)-3-methyl-4,5-2H-1,2,4-triazol-one(153833-78-4)

Safety Data

• Hazardous Substances Data: 153833-78-4(Hazardous Substances Data)

Usage

General Description

1-(2-Fluorophenyl)-3-methyl-4,5-2H-1,2,4-triazol-one, also known as fluconazole, is an antifungal medication used to treat a variety of fungal infections. It works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to the disruption of the membrane and ultimately the death of the fungus. Fluconazole is commonly used to treat infections such as candidiasis, cryptococcosis, and histoplasmosis, and is available in different formulations including oral, intravenous, and topical. Its broad spectrum of activity, relatively low toxicity, and good bioavailability make it a popular choice for the treatment of fungal infections. However, it may have side effects such as nausea, headache, and liver damage in some individuals.