153899-37-7

Basic information

• Product Name: (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid
• CAS NO: 153899-37-7
• Molecular Weight: 264.321
• Mol File: 153899-37-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid(153899-37-7)
• EPA Substance Registry System: (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid(153899-37-7)

Safety Data

• Hazardous Substances Data: 153899-37-7(Hazardous Substances Data)

Upstream product

• 153899-36-6 (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enal 
• 141546-68-1 4-O-benzoyl-2-deoxy-1-O-methylsulfonyl-2-C-methyl-3-O-methyl-L-threitol 
• 153899-35-5 Benzoic acid (2R,3R)-2-methoxy-3-methyl-4-oxo-butyl ester 
• 141546-66-9 1,6-di-O-benzoyl-3-deoxy-3-C-methyl-2-O-methyl-L-altritol 
• 141546-69-2 (3S,4R)-5-benzyloxy-4-methoxy-3-methylpentanenitrile 
• 141546-67-0 4-O-benzoyl-2-deoxy-2-C-methyl-3-O-methyl-L-threitol 
• 141546-71-6 (3S,4R)-4-Methoxy-3-methyl-5-oxo-pentanenitrile 
• 141546-70-5 (3S,4R)-5-hydroxy-4-methoxy-3-methylpentanenitrile 
• 170081-25-1 (2S,3S)-1-tert-butyldimethylsiloxy-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 
• 170081-24-0 (2S,3S)-1-tert-butyldimethylsiloxy-3-hydroxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 
• 151121-11-8 (2S,3S)-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1,3-diol 
• 150932-10-8 (2S,3S)-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1-ol 
• 169898-61-7 (+/-)-5-(4-methoxyphenyl)-2-methyl-3-oxo-(4E)-penten-1-ol 
• 126753-78-4 methyl 5-(4-methoxyphenyl)-2-methyl-3-oxopent-4-enoate 

Downstream Products

• 153899-38-8 (E)-(3S,4S)-2-[1-Hydroxy-meth-(E)-ylidene]-4-methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid methyl ester 
• 130640-32-3 (-)-oudemansin X 

Relevant articles and documents

Total synthesis of (±)-, (-)-, and (+)-oudemansin X

Three kinds of oudemansin X, (-)-1, (+)-1 and (±)-1, were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8, using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.

Total Synthesis of Antibiotic (-)-Oudemansin X Utilizing L-Quebrachitol as a Chiral Pool

The stereoselective conversion of naturally occurring optically active cyclitol, L-quebrachitol (2), into antifungal (E)-β-methoxyacrylate, oudemansin X is described.This synthesis fully confirmed the proposed absolute configuration of the antibiotic and