1539320-94-9

Basic information

• Product Name: (R)-methyl 2-((S)-1-(2-((R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanamido)benzoyl)pyrrolidine-2-carboxamido)-4-methylpentanoate
• CAS NO: 1539320-94-9
• Molecular Weight: 590.676
• Mol File: 1539320-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-methyl 2-((S)-1-(2-((R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanamido)benzoyl)pyrrolidine-2-carboxamido)-4-methylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-methyl 2-((S)-1-(2-((R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanamido)benzoyl)pyrrolidine-2-carboxamido)-4-methylpentanoate(1539320-94-9)
• EPA Substance Registry System: (R)-methyl 2-((S)-1-(2-((R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanamido)benzoyl)pyrrolidine-2-carboxamido)-4-methylpentanoate(1539320-94-9)

Safety Data

• Hazardous Substances Data: 1539320-94-9(Hazardous Substances Data)

Upstream product

• 5115-65-1 (R)-N-phthaloylvaline 
• 1539320-56-3 (S)-methyl 2-((R)-1-(2-((tert-butoxycarbonyl)amino)benzoyl)-pyrrolidine-2-carboxamido)-4-methylpentanoate 
• 72212-78-3 (R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanoyl chloride 
• 15136-17-1 (S)-tert-butyl 2-(((R)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 
• 23032-21-5 D-leucine methyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 

Downstream Products

• 1539320-47-2 (R)-N-((S)-4-methyl-1-(methylamino)-1-oxopentan-2-yl)-1-(2-((S)-3-methyl-2-pivalamidobutanamido)benzoyl)pyrrolidine-2-carboxamide 

Relevant articles and documents

Formation of a Pseudo-β-hairpin motif utilizing the Ant-pro reverse turn: Consequences of stereochemical reordering

Herein, we report a special case of pseudo-β-hairpin formation by tetrapetide sequences featuring a two-membered Ant-Pro dipeptide motif (Ant = anthranilic acid and Pro = proline) at the loop region. These folded structures uniquely feature the presence of C9- and C17-H-bonding patterns at reverse turn and interstrand regions, respectively. Their hairpin nucleation and folding propensities have been expounded using solution and solid state studies of distinct stereochemically altered sequences.