15409-60-6 Usage
Description
2-[(dimethylamino)methyl]cyclohexan-1-one, also known as 2-(Bismethyl)aminomethylcyclohexanone, is an organic compound with a unique chemical structure that features a cyclohexanone ring with a dimethylaminomethyl group attached to the 2-position. 2-[(dimethylamino)methyl]cyclohexan-1-one is known for its potential applications in the pharmaceutical industry due to its ability to act as an intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
2-[(dimethylamino)methyl]cyclohexan-1-one is used as an intermediate in the synthesis of O-Desmethyl Tramadol Hydrochloride (D294750), which is an optically active metabolite of Tramadol. This application is significant because O-Desmethyl Tramadol Hydrochloride is known for its analgesic properties, making it a valuable compound in the development of pain relief medications.
Synthesis Reference(s)
Journal of the American Chemical Society, 98, p. 6715, 1976 DOI: 10.1021/ja00437a058Synthetic Communications, 14, p. 585, 1984 DOI: 10.1080/00397918408059581
Check Digit Verification of cas no
The CAS Registry Mumber 15409-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,0 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15409-60:
(7*1)+(6*5)+(5*4)+(4*0)+(3*9)+(2*6)+(1*0)=96
96 % 10 = 6
So 15409-60-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H5BrN2/c1-7-3-2-6-4(7)5/h2-3H,1H3
15409-60-6Relevant articles and documents
Stereocontrolled Syntheses of Mannich Bases and γ-Amino Alcohols
Risch, Nikolaus,Esser, Achim
, p. 233 - 238 (2007/10/02)
The reaction of enantiomerically pure SMP enamines 2 with iminium tetrachloroaluminates 3 yields optically active Mannich bases 4.Diastereoselective reduction of 4 gives γ-amino alcohols 5 with the desired configuration. Key Words: Mannich bases / Enamines / Iminium salts / γ-Amino alcohols
