154229-36-4 Usage
Description
Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate is an organic compound that serves as a byproduct in the synthesis of Abiraterone Acetate. It is characterized by its yellow syrup-like appearance and possesses unique chemical properties that make it valuable in various applications.
Uses
Used in Pharmaceutical Industry:
Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate is used as an intermediate in the synthesis of Abiraterone Acetate, a drug used for the treatment of metastatic castration-resistant prostate cancer. Its role in the pharmaceutical industry is crucial for the production of this life-saving medication.
Used in Chemical Research:
Due to its unique chemical properties, Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate can be utilized in various chemical research applications. It may serve as a starting material or a catalyst in the development of new compounds and pharmaceuticals, contributing to the advancement of scientific knowledge and innovation in the field.
Used in Drug Synthesis:
Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate is used as a key component in the synthesis of other drugs and pharmaceutical compounds. Its unique structure and properties make it a valuable asset in the development of novel therapeutic agents, potentially leading to the discovery of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 154229-36-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,2,2 and 9 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154229-36:
(8*1)+(7*5)+(6*4)+(5*2)+(4*2)+(3*9)+(2*3)+(1*6)=124
124 % 10 = 4
So 154229-36-4 is a valid CAS Registry Number.
154229-36-4Relevant articles and documents
PROCESS FOR MAKING THE 17-TRIFLATE INTERMEDIATE OF ABIRATERONE-3-ACETATE
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Page/Page column 16; 17, (2014/05/24)
The present invention relates to a process for making the compound 3β-acetoxy- androsta-5,16-dien-17-yl trifluoromethanesulfonate of formula (5) and is characterized in that dehydroepiandrosterone-3-acetate of formula (2) is reacted with a triflating agent, preferably trifluoromethanesulfonic anhydride, in an inert solvent in the absence of an organic base.
17-substituted steroids useful in cancer treatment
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, (2008/06/13)
Compounds of the general formula (1) STR1 wherein X represents the residue of the A, B and C rings of a steroid, R represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, R 14 represents a hydrogen atom and R 15 represents a hydrogen atom or an alkyl or alkoxy group of 1-4 carbon atoms, or a hydroxy or alkylcarbonyloxy group of 2 to 5 carbon atoms or R 14 and R 15 together represent a double bond, and R 16 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, in the form of the free bases or phannaceutically acceptable acid addition salts, are useful for treatment of androgen-dependent disorders, especially prostatic cancer, and also oestrogen-dependent disorders such as breast cancer.
