154260-25-0

Basic information

• Product Name: 3,5-DICHLORO-2-METHOXYACETOPHENONE
• Synonyms: 3,5-DICHLORO-2-METHOXYACETOPHENONE
• CAS NO: 154260-25-0
• Molecular Formula: C₉H₈Cl₂O₂
• Molecular Weight: 219.06
• Mol File: 154260-25-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-DICHLORO-2-METHOXYACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLORO-2-METHOXYACETOPHENONE(154260-25-0)
• EPA Substance Registry System: 3,5-DICHLORO-2-METHOXYACETOPHENONE(154260-25-0)

Safety Data

• Hazardous Substances Data: 154260-25-0(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 6341-97-5 1,3-dichloro-4-acetoxybenzene 
• 3321-92-4 1-(3,5-dichloro-2-hydroxyphenyl)-ethanone 
• 74-88-4 methyl iodide 
• 120-83-2 2,4-dichlorophenol 

Downstream Products

• 108980-09-2 3',5'-dichloro-4,2'-dimethoxy-trans-chalcone 
• 101735-98-2 3',5'-dichloro-3,4,2'-trimethoxy-trans-chalcone 
• 108981-46-0 3',5'-dichloro-2,2'-dimethoxy-trans-chalcone 

Relevant articles and documents

Iridium-Catalyzed C(sp3)?H Addition of Methyl Ethers across Intramolecular Carbon–Carbon Double Bonds Giving 2,3-Dihydrobenzofurans

Intramolecular addition of an O-methyl C(sp3)?H bond across a carbon-carbon double bond occurs in the iridium-catalyzed reaction of methyl 2-(propen-2-yl)phenyl ethers. The Ir/(S)-DTBM-SEGPHOS catalyst promotes the reaction efficiently in toluene at 110–135 °C to afford 3,3-dimethyl-2,3-dihydrobenzofurans. Enantioselective C(sp3)?H addition is achieved in the reaction of methyl 2-(1-siloxyethenyl)phenyl ethers, affording enantioenriched 3-hydroxy-2,3-dihydrobenzofuran derivatives with up to 96% ee. (Figure presented.).