154356-96-4 Usage
Description
(4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate Impurity) is a photoproduct derived from the antihyperlipoproteinemic drug Fenofibrate (F248640). It is a chemical compound that results from the interaction of Fenofibrate with light, leading to a structural alteration in the molecule.
Uses
Used in Pharmaceutical Industry:
(4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate Impurity) is used as a reference compound for the quality control and analysis of Fenofibrate in the pharmaceutical industry. Its presence in the drug formulation can be monitored and controlled to ensure the safety, efficacy, and purity of the antihyperlipoproteinemic drug Fenofibrate.
Used in Research and Development:
In the field of research and development, (4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate Impurity) serves as a valuable compound for studying the photochemical reactions and stability of Fenofibrate. This understanding can help in the development of improved drug formulations and the optimization of storage and handling conditions to minimize the formation of impurities.
Used in Quality Control Laboratories:
(4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate Impurity) is utilized as a reference material in quality control laboratories to validate and calibrate analytical methods for the detection and quantification of impurities in Fenofibrate drug products. This ensures that the drug meets the required standards for quality and safety before it is released for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 154356-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,3,5 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154356-96:
(8*1)+(7*5)+(6*4)+(5*3)+(4*5)+(3*6)+(2*9)+(1*6)=144
144 % 10 = 4
So 154356-96-4 is a valid CAS Registry Number.
154356-96-4Relevant articles and documents
A laser flash photolysis study of fenofibric acid in aqueous buffered media: Unexpected triplet state inversion in a derivative of 4-alkoxybenzophenone
Cosa, Gonzalo,Purohit,Scaiano,Bosca, Francisco,Miranda, Miguel A.
, p. 193 - 200 (2002)
Laser excitation of aqueous solutions of fenofibric acid (FA) at pH 7.4 show the formation of two reaction intermediates, the triplet state and the hydrated electron. The former is longer lived in water than in acetonitrile; its anionic form decays irreve
Direct Hydrodecarboxylation of Aliphatic Carboxylic Acids: Metal- and Light-Free
Burns, David J.,Lee, Ai-Lan,McLean, Euan B.,Mooney, David T.
supporting information, p. 686 - 691 (2022/01/28)
A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.
