15437-14-6

Basic information

• Product Name: N-(4-ETHOXYPHENYL)BENZAMIDE
• Synonyms: N-(4-ETHOXYPHENYL)BENZAMIDE;P-BENZOPHENETIDIDE
• CAS NO: 15437-14-6
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.2851
• Mol File: 15437-14-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 307.1°Cat760mmHg
• Flash Point: 139.5°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 0.000741mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: N-(4-ETHOXYPHENYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-ETHOXYPHENYL)BENZAMIDE(15437-14-6)
• EPA Substance Registry System: N-(4-ETHOXYPHENYL)BENZAMIDE(15437-14-6)

Safety Data

• Hazardous Substances Data: 15437-14-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H15NO2/c1-2-18-14-10-8-13(9-11-14)16-15(17)12-6-4-3-5-7-12/h3-11H,2H2,1H3,(H,16,17)

Upstream product

• 62869-42-5 para-ethoxybenzoyl cyanide 
• 62-53-3 aniline 
• 98-88-4 benzoyl chloride 
• 100-29-8 1-ethoxy-4-nitrobenzene 
• 7719-09-7 thionyl chloride 
• 60-29-7 diethyl ether 
• 92850-70-9 4-ethoxy-benzophenone-seqtrans-oxime 
• 157124-43-1 1-(4-ethoxyphenyl)-1H-tetrazole 
• 100-52-7 benzaldehyde 
• 93-89-0 benzoic acid ethyl ester 
• 156-43-4 4-Ethoxyaniline 
• 699-08-1 1-ethoxy-4-iodobenzene 
• 55-21-0 benzamide 
• 62-44-2 4-ethoxyacetanilide 

Downstream Products

• 1934-89-0 N-(4-ethoxy-phenyl)-benzimidoyl chloride 
• 150313-07-8 N-(4,4-Diethoxy-cyclohexa-2,5-dienylidene)-benzamide 
• 129201-43-0 N-Benzoyl-1,4-benzoquinone imine 
• 156-43-4 4-Ethoxyaniline 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Direct Amidation of Esters by Ball Milling**

The direct mechanochemical amidation of esters by ball milling is described. The operationally simple procedure requires an ester, an amine, and substoichiometric KOtBu and was used to prepare a large and diverse library of 78 amide structures with modest to excellent efficiency. Heteroaromatic and heterocyclic components are specifically shown to be amenable to this mechanochemical protocol. This direct synthesis platform has been applied to the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals as well as the gram-scale synthesis of an active pharmaceutical, all in the absence of a reaction solvent.

TBHP-mediated highly efficient dehydrogenative cross-oxidative coupling of methylarenes with acetanilides

A TBHP-mediated dehydrogenative cross-oxidative-coupling approach has been developed for the synthesis of N-arylbenzamides from methylarenes and acetanilides. This cross-coupling method is free of transition metal catalysts and ligands, and no extra organic solvents are required, which make it an useful and attractive strategy for the straightforward construction of C-N bonds. Besides, this conversion is an important complement to the conventional C-N forming strategies.

Synthesis of amides through an oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions

A simple, inexpensive and efficient one-pot synthesis of amides was achieved in good yields via the direct oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions.