154377-07-8

Basic information

• Product Name: diethyl phenyl(methylsulfonyl)malonate
• Synonyms: diethyl phenyl(methylsulfonyl)malonate
• CAS NO: 154377-07-8
• Molecular Weight: 314.359
• Mol File: 154377-07-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl phenyl(methylsulfonyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl phenyl(methylsulfonyl)malonate(154377-07-8)
• EPA Substance Registry System: diethyl phenyl(methylsulfonyl)malonate(154377-07-8)

Safety Data

• Hazardous Substances Data: 154377-07-8(Hazardous Substances Data)

Upstream product

• 82751-11-9 diethyl (methylsthio)phenylmalonate 

Downstream Products

• 82751-11-9 diethyl (methylsthio)phenylmalonate 
• 83-13-6 diethyl 2-phenylmalonate 

Relevant articles and documents

Selective sulfenylative desulfonylation or decarbalkoxylation of α-sulfonyl malonates with DABCO or Bu3N: Reactivity and conformational analysis

The study on reactivity of severalαsubstituted αsulfonyl malonates toward 1,4-diazabicyclo[2.2.2]octane (DABCO) and Bu3N is described. The reactivity with DABCO revealed the possible competition between decarbalkoxylation and unexpected desulfonylation, depending on the-substituent, because of sterical hindrance around the electrophilic centers (SO2 and CO2R). The derivatives with crowded α-substituents suffer selective desulfonylation, and a novel and efficient desulfonylation method can be proposed. The dependence of the reactivity ofα-sulfonyl malonates on the sterical hindrance around the electrophilic centers is confirmed by conformational analysis (Macromodel/MM2* and Mopac/MP3). The carbanionic mechanism is proved because the corresponding protonated, deuterated, and sulfenylated products were obtained by addition of the corresponding electrophilic agents. Bu3N showed itself to be a novel selective decarbalkoxylation agent for any-substituted-sulfonyl malonate.