154387-90-3

Basic information

• Product Name: 1H-Benzimidazole,1-(propoxymethyl)-(9CI)
• Synonyms: 1H-Benzimidazole,1-(propoxymethyl)-(9CI)
• CAS NO: 154387-90-3
• Molecular Formula: C11H14N2O
• Molecular Weight: 190.24166
• Product Categories: BENZIMIDAZOLE
• Mol File: 154387-90-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,1-(propoxymethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-(propoxymethyl)-(9CI)(154387-90-3)
• EPA Substance Registry System: 1H-Benzimidazole,1-(propoxymethyl)-(9CI)(154387-90-3)

Safety Data

• Hazardous Substances Data: 154387-90-3(Hazardous Substances Data)

Upstream product

• 51-17-2 benzoimidazole 
• 3587-57-3 chloromethyl propyl ether 
• 71-23-8 propan-1-ol 
• 75-15-0 carbon disulfide 
• 220-52-0 16H,13H-5:12,7:14-dimethanedibenzo[d,i]-[1,3,6,8]tetraazecine 
• 50-00-0 formaldehyd 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Nano indium oxide-catalyzed domino reaction for the synthesis of N-alkoxylated benzimidazoles

A convenient method has been developed for the selective synthesis of N-alkoxylated benzimidazole derivatives by the cyclocondensation reaction of simple ortho-phenylenediamine, formaldehyde and alcohols in presence of indium oxide nanoparticles as catalyst. The alcohol acts as reactant as well as solvent in this reaction. No other solvents or additives have been used for this reaction. The catalyst can be reused several times without significant loss of catalytic activity. A probable reaction mechanism has been proposed based on some control experiments.

1-ALKOXYMETHYL- AND 1-ALKYLTHIOMETHYL-4-DIMETHYLAMINOPYRIDINIUM CHLORIDES

ROCH2Cl or RSCH2Cl reacts with DMAP to form stable pyridinium chlorides.Reaction of these chlorides with NaOH produces the corresponding 4-pyridones.N-Alkoxymethylation of a free NH group of azoles is developed from 1-alkoxymethyl-4-dimethylaminopyridiniu