15441-67-5

Basic information

• Product Name: 3-Hexyn-2-one, 5-hydroxy-
• CAS NO: 15441-67-5
• Molecular Formula: C6H8O2
• Molecular Weight: 112.128
• Mol File: 15441-67-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 3-Hexyn-2-one, 5-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hexyn-2-one, 5-hydroxy-(15441-67-5)
• EPA Substance Registry System: 3-Hexyn-2-one, 5-hydroxy-(15441-67-5)

Safety Data

• Hazardous Substances Data: 15441-67-5(Hazardous Substances Data)

Upstream product

• 271598-41-5 5-trimethylsilanyloxy-hex-3-yn-2-ol 
• 3031-66-1 3-hexyn-2,5-diol 
• 65983-88-2 5-tetrahydropyran-2-yloxy-hex-3-yn-2-one 

Downstream Products

• 54415-31-5 hex-3-yne-2,5-dione 
• 63359-63-7 2,5-dimethyl-3-methylsulfanyl-furan 
• 57556-12-4 3-methoxy-2,5-dimethyl-furan 
• 28588-73-0 bis (2,5-dimethyl-furan-3-yl)-disulfide 
• 61197-06-6 methyl 2,5-dimethylfur-3-yl disulfide 
• 55764-23-3 3-mercapto-2,5-dimethylfuran 
• 161637-38-3 C₁₃H₁₂⁽²⁾H₂O₃ 
• 161637-33-8 (E)-5-benzoyloxyhex-3-en-2-one 
• 161637-34-9 (Z)-5-benzoyloxyhex-3-en-2-one 
• 24068-54-0 3-acetyl-5-methylisoxazole 
• 1028277-45-3 Benzoic acid 1-methyl-4-oxo-pent-2-ynyl ester 
• 55764-22-2 S-(2,5-dimethylfur-3-yl) thioacetate 

Relevant articles and documents

A convenient preparation of 3-Acetyl-5-methylisoxazole

Starting from 2,5-hexanedione (4), a one-pot preparation of 3-acetyl-5-methylisoxazole (1) is described. 3-Acetyl-5-methylisoxazole (1) is a useful compound for the preparation of 3-oxobutyronitrile (10) and for 3-vinyl-(5-methyl isoxazolyl) ketone (2).

A new approach to 1-substituted-1,2-alkadiene-phosphonates III: Synthesis of 2-keto-5-methyl-3,4-hexadienyl-3-phosphonate dimethyl esters

Abstract: The synthesis of the titled compounds have been discussed. Copyright Taylor & Francis Inc.

4- (SULFANYL-PYRIMIDIN-4-YLMETHYL) -MORPHOLINE DERIVATIVES AND RELATED COMPOUNDS AS GABA RECEPTOR LIGANDS FOR THE TREATMENT OF ANXIETY, DEPRESSION AND EPILEPSY

The present invention relates to compounds of Formula (I) wherein X is-S-or-NH-; R1 is alkyl, alkenyl, arylalkyl, arylalkenyl or aryl-O-alkyl, wherein the aryl groups are optionally substituted by one or more substituents, selected from the group consisting of lower alkyl, lower alkoxy, halogen or lower halogen-alkyl; R2 is hydrogen, lower alkyl or cycloalkyl; R3 /R4 may form together with the N-atom to which they are attached a non aromatic5, 6 or 7 membered ring, which may contain in addition to the N-atom one additional heteroatom selected from the group consisting of O, S or N, and wherein the ring is optionally substituted by hydroxy, lower alkyl, lower alkoxy,-NR2,-CONR2,-CO-lower alkyl or benzyl; or may form together with the N-atom to which they are attached a heterocyclic ring system, containing at least two rings and which may contain one or two additional heretoatoms, selected from the group consisting of N or O; R is hydrogen or lower alkyl; R5 is hydrogen or lower alkyl; and to pharmaceutically suitable acid addition salts thereof. It has been found that the compounds are active on the GABAB receptor and therefore useful for the treatment of anxiety, depression, epilepsy, schizophrenia, cognitive disorders, spasticity and skeletal muscle rigidity, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, cerebral palsy, neuropathic pain and craving associated with cocaine and nicotine, psychosis, panic disorder, posttraumatic stress disorders or gastro-intestinal disorders.