1544274-14-7

Basic information

• Product Name: 3-methyl-5-(4-nitrophenyl)-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione
• Synonyms: 3-methyl-5-(4-nitrophenyl)-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione
• CAS NO: 1544274-14-7
• Molecular Weight: 409.425
• Mol File: 1544274-14-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-5-(4-nitrophenyl)-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-5-(4-nitrophenyl)-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(1544274-14-7)
• EPA Substance Registry System: 3-methyl-5-(4-nitrophenyl)-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(1544274-14-7)

Safety Data

• Hazardous Substances Data: 1544274-14-7(Hazardous Substances Data)

Upstream product

• 21236-97-5 3-methyl-6-aminouracil 
• 555-16-8 4-nitrobenzaldehdye 
• 103-72-0 phenyl isothiocyanate 

Relevant articles and documents

An efficient and regioselective one-pot multi-component synthesis of pyrimido[4,5-d]pyrimidine derivatives in water

Pyrimido[4,5-d]pyrimidine derivatives 4 have been prepared in an efficient and regioselective manner in water via multi-component reaction of isothiocyanate 1, aromatic aldehyde 2, N,N-dimethyl-6-amino uracil 3 in the presence of p-toluenesulfonic acid (p-TSA) as a Lewis acid catalyst.