154470-43-6Relevant articles and documents
Hofmann-type elimination in the efficient N-alkylation of azoles: Imidazole and benzimidazole
Horvath
, p. 102 - 106 (1994)
A simple and efficient preparation of 1-substituted 1H-azoles (imidazole and benzimidazole) has been developed, which involves a selective Hofmann-type elimination of the 2-cyanoethyl group from the azolium salts obtained by the reaction of halides with 1H-imidazole-1-propanenitrile and 1H-benzimidazole-1-propanenitrile. Overall yields of 1-substituted 1H-azoles decreased in the order: primary alkyl halides ≥ allylhalides ≥ secondary alkyl halides ≥ benzyl halides > α-keto halides, in relation to the alkylating agent, and imidazole ≥ benzimidazole, in relation to the azole, respectively.
Non-symmetrically p-nitrobenzyl- and p-cyanobenzyl-substituted N-heterocyclic carbene-silver(I) complexes: synthesis, characterization and antibacterial studies
Subramanya Prasad,Shahini,Patil, Shivaputra A.,Huang, Xiaojun,Bugarin, Alejandro,Patil, Siddappa A.
, p. 600 - 614 (2017)
Various nitro/nitrile-functionalized benzimidazol-2-ylidene carbene complexes of silver(I) (7a–d and 11a–d) were synthesized by combination of 1-allyl/1-isopropyl/1-sec-butyl/1-isopentyl-3-(nitro/cyano-benzyl)-3H-benzimidazol-1-ium hexafluorophosphate (6a
