154669-73-5

Basic information

• Product Name: (R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE
• Synonyms: N-ACETYL-(4R)-PHENYL-2-OXAZOLIDINONE;(R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE;(4R)-3-ACETYL-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
• CAS NO: 154669-73-5
• Molecular Formula: C11H11NO3
• Molecular Weight: 205.21
• Mol File: 154669-73-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 383.7°Cat760mmHg
• Flash Point: 185.9°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.562
• PKA: 12.05±0.40(Predicted)
• CAS DataBase Reference: (R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE(154669-73-5)
• EPA Substance Registry System: (R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE(154669-73-5)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 22-24/25
• Hazardous Substances Data: 154669-73-5(Hazardous Substances Data)

Usage

General Description

(R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE is a chemical compound with the molecular formula C11H11NO3. It is a type of oxazolidinone, which is a class of organic compounds containing a five-membered oxazolidinone ring. This specific compound is a chiral molecule, meaning it has a non-superimposable mirror image, and is commonly referred to as a chiral auxiliary in organic chemistry. It has various applications in asymmetric synthesis and as a building block for the synthesis of pharmaceuticals and other organic compounds. Additionally, it exhibits antibacterial activity and has been studied for its potential as an antibacterial agent. Overall, "(R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE" is a versatile and important compound with various applications in organic chemistry and pharmaceutical research.

InChI:InChI=1/C11H11NO3/c1-8(13)12-10(7-15-11(12)14)9-5-3-2-4-6-9/h2-6,10H,7H2,1H3/t10-/m1/s1

Upstream product

• 156386-82-2 trans-γ-3-benzoylprop-2-en-1-ol 
• 1449434-92-7 (R)-3-(4-chlorophenylsulfonyl)-4-(2-oxo-2-phenylethyl)oxazolidin-2-one 
• 321983-60-2 (4S,5S,6R)-4-hydroxymethyl-5-iodo-6-phenyl-1,3-oxazin-2-one 
• 676473-33-9 (4R)-4-[(2S)-2-hydroxy-2-phenylethyl]-1,3-oxazolidin-2-one 
• 132682-24-7 (S)-(-)-4-iodomethyl-2-oxazolidinone 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Novel enantiomerically pure 2-amino-1,4-diols from chiral 4-hydroxymethyl-5-iodo-1,3-oxazin-2-ones

Reduction of (4S,5S,6S)-4-hydroxymethyl-5-iodo-6-methyl-1,3-oxazin-2-one 2a and (4S,5S,6R)-4-hydroxymethyl-5-iodo-6-phenyl-1,3-oxazin-2-one 2b with tributyltin hydride in ethanol afforded 1,3-oxazin-2-one 3a and 1,3-oxazolidin-2-one 4b, respectively. Hydr

Preparation and reactivity of chiral β-amino-alkylzinc iodides and related configurationally stable zinc organometallics

Several zinc organometallics bearing at the β-position a carbamate or an amido function with an acidic N-H group were prepared using the direct insertion of zinc dust into the corresponding alkyl iodides in THF or THF:DMSO mixtures. Most of the starting iodides were obtained from natural α-amino acids and the resulting zinc species afforded after transmetalation with CuCN.2LiCl and reaction with a selection of relatively reactive electrophiles a variety of polyfunctional 1,2-amino alcohol derivatives and carbamates in optically pure form. Several secondary β-amido alkyl iodides were converted to the corresponding chiral zinc reagents and trapped with electrophiles. The configurational stability of chiral secondary organozinc compounds and the stereochemical course of their reactions were examined.